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Clinical application of 3D slicer reconstruction and 3D printing localization combined with neuroendoscopy technology in VPS surgery.
Sci Rep
January 2025
Department of Neurosurgery, Renmin Hospital of Wuhan University, No. 238, Jiefang Road, Wuchang District, Wuhan, 430060, Hubei, China.
To explore techniques, advantages and disadvantages of 3D Slicer reconstruction and 3D printing localization technology combined with transcranial neuroendoscopy in ventriculoperitoneal shunt surgery. Retrospective analysis of clinical data of patients with hydrocephalus treated by ventriculoperitoneal shunt surgery using 3D Slicer reconstruction and 3D printing positioning technology combined with transcranial neuroendoscopy in our hospital from October 2021 to March 2023. A total of 33 patients with complete data were collected, including 19 males and 14 females, aged 10-81 years.
View Article and Find Full Text PDFMultisystem clinicopathologic and genetic analysis of MELAS.
Orphanet J Rare Dis
December 2024
Department of Pathology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Zhongshan Road 321#, Nanjing, 210008, Jiangsu, China.
Background And Objectives: Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome is a maternally inherited mitochondrial disorder that mostly affects the central nervous system and skeletal muscle. This study provides a comprehensive summary of the clinical symptoms, multisystemic pathogenesis, and genetic characteristics of MELAS syndrome. The aim was to improve comprehension of clinical practice and gain a deeper understanding of the latest pathophysiological theories.
View Article and Find Full Text PDFA Real-World Study on Adverse Reactions of Belimumab Based on the FDA Adverse Event Reporting System Database.
Pharmacoepidemiol Drug Saf
October 2024
Hunan Drug Inspection Center, Changsha, Hunan Province, China.
Article Synopsis
- The investigation analyzes data from the FDA's Adverse Event Reporting System (FAERS) to assess real-world adverse reactions related to Belimumab, aiming to enhance clinical safety in its use.
- Over 19,825 adverse drug event reports pertaining to Belimumab were analyzed, revealing that the majority of affected patients were females aged 18 to 64.9 years, with systemic disorders and infections being the most reported issues.
- The study highlights significant adverse reactions not listed on product labeling, such as hypersensitivity and herpes zoster infections, suggesting the need for improved communication on these risks in clinical settings.*
Developmentally controlled subcellular remodeling and VND-initiated vacuole-executed PCD module shape xylem-like cells in peat moss.
Commun Biol
October 2024
School of Life Sciences, East China Normal University, 200241, Shanghai, China.
Peat moss (Sphagnum) is a non-vascular higher plant with unique xylem-like hyaline (H) cells that are accompanied by photosynthetic chlorophyllous cells. These cellular structures play crucial roles in water storage and carbon sequestration. However, it is largely unknown how peat moss develops the H cells.
View Article and Find Full Text PDFUnlabelled: Cerebrovascular networks contain a unique region of interconnected capillaries known as the blood-brain barrier (BBB). Positioned between upstream arteries and downstream veins, these microvessels have unique structural features, such as the absence of vascular smooth muscle cells (vSMCs) and a relatively thin basement membrane, to facilitate highly efficient yet selective exchange between the circulation and the brain interstitium. This vital role in neurological health and function has garnered significant attention from the scientific community and inspired methodology for enriching BBB capillaries.
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