This article, written by several authors, describes the birth and early development of the nephrology at Molinette Hospital in Torino, Italy. In particular, it supplies important information on Antonio Vercellone, very motivated and innovative clinician and one of the fathers of Italian nephrology, and on Giuseppe Piccoli, his right-hand man and then his successor. This article also shows the strong professional and human engagement that was requested to the young doctors who, in the early Sixties and Seventies of the past century, had chosen to devote their professional lives to the patients with kidney diseases: from endless workdays without schedules to the anguish caused by the shortage of artificial kidneys to the cure of very fragile and unfortunate patients, and much more.
Introduction: Prostate cancer incidence in immunosuppressed transplant recipients increases as life expectancy improves in this population. However, the management of treatments and immunosuppressive (IS) regimens for solid organ transplant recipients diagnosed with prostate cancer remains poorly defined. Therefore, we conducted a multicentric study to investigate these parameters more thoroughly.
The study aimed to develop a machine-learning model to predict the risk of sepsis following retrograde intrarenal surgery (RIRS) for kidney stones, including data from 1,552 patients across 16 centers.*
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Inclusion criteria for patients were specified, and certain conditions like concomitant ureteral stones were excluded, with antibiotic treatments used where applicable.*
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The Random Forest algorithm outperformed other machine-learning models, achieving high precision, recall, and accuracy, and a web-based version of the predictive tool is available for use in clinical settings.*
IgA nephropathy and IgA vasculitis with nephritis are kidney conditions that can occur in kids, but they're pretty rare.
Unlike adults, children often show more severe symptoms quickly, like blood in their urine, and their kidneys look more inflamed when doctors check.
There's not a lot of good information on how to treat these conditions because they're different in kids, and experts from around the world are trying to figure out better ways to help affected children.
* In a study involving 947 children with IgAN, the revised tool outperformed the original in terms of model fit and predictive accuracy for 4-year outcomes, showing enhanced calibration and statistical values.
* The findings indicated that kidney function (eGFR) trajectories were non-linear, with higher-risk children showing a faster decline, suggesting that the updated prediction should be used for ongoing risk assessment after one or two years following biopsy.
