Hyperleukocytosis, a white blood cell count greater than 100,000/mcl, can be associated with the following three primary oncologic emergencies: leukostasis, disseminated intravascular coagulation, and tumor lysis syndrome. Th.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1188/23.CJON.589-593 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Emergencies in Hematology: Why, When and How I Treat?
J Clin Med
December 2024
Hematology Unit with BMT, A.O.U. Policlinico "G.Rodolico-San Marco", 95123 Catania, Italy.
Hematological emergencies are critical medical conditions that require immediate attention due to their rapid progression and life-threatening nature. As various examples, hypercalcemia, often associated with cancers such as multiple myeloma, can lead to severe neurological and cardiac dysfunction. Hyperleukocytosis, common in acute myeloid leukemias, increases the risk of leukostasis and multiorgan failure.
View Article and Find Full Text PDFExtreme hyperleukocytosis (Leukocyte count >200 × 10/L) in an adolescent young adult (AYA) patient with B-ALL could result in mild symptoms of leukostasis. Hyperleukocytosis requires prompt initiation of therapy with adequate hydration, cytoreduction and prevention of tumor lysis. Ph + B-ALL may present with extreme hyperleukocytosis and may be resistant to initial pre-phase therapy.
View Article and Find Full Text PDFST elevation myocardial infarction as presenting feature of acute myeloid leukemia.
Med J Armed Forces India
December 2024
Professor (Clinical Hematology), Army Hospital (R & R), New Delhi, India.
A 35-year-old male patient with acute myeloid leukemia (AML), with hyperleukocytosis, presented with acute myocardial infarction. The individual had acute onset chest pain and reached the hospital within the window period. His electrocardiogram (ECG) revealed ST elevated myocardial infarction (STEMI), ST elevated myocardial infarction, and thrombolysis was performed.
View Article and Find Full Text PDFCase Report: A case of infantile acute hyperleukocytic leukemia treated by leukapheresis.
Front Pediatr
December 2024
Department of Hematology and Oncology, Dalian Women and Children's Medical Group, Dalian, China.
Leukapheresis is a treatment used to reduce leukocytes to decrease the number of white blood cells in circulation and prevent the risks of hyperviscosity and cerebrovascular and pulmonary leukostasis. We present a case of pro-B-cell acute lymphoblastic leukemia (ALL) with hyperleukocytosis in a 6-month-old infant, characterized by a positive KMT2A/AFF1 fusion gene with a leukocyte count of 1,755 × 10/L. After two consecutive sessions of leukapheresis, the white blood cell count decreased to 55 × 10/L.
View Article and Find Full Text PDFLeukoreduction in a dog with acute leukemia.
J Vet Intern Med
December 2024
Friendship Hospital for Animals, Washington, District of Columbia, USA.
A 9-year-old male castrated golden retriever cross was evaluated for an acute onset of ataxia. A complete blood count revealed marked leukocytosis, anemia, and thrombocytopenia. Leukocytosis was characterized by marked lymphocytosis, monocytosis, neutropenia, and eosinopenia.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!