The authors present a striking case of a patient experiencing a lichenoid drug eruption secondary to immunotherapy, curiously sparing scarred skin from past burns. We observed vastly higher amounts of inflammatory lymphoid cells staining for PD-1; 70% in skin with a lichenoid drug reaction and 50% in scarred skin. The lack of a lichenoid reaction at sites of scarred skin may indicate that a basement membrane component may be causative for a lichenoid drug eruption.
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http://dx.doi.org/10.1111/ajd.14192 | DOI Listing |
Cutis
October 2024
Madelyn M. Class is from the Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania. Drs. McCoy, Hafeez, and Westheim are from the Department of Dermatology, St. Luke's University Health Network, Easton, Pennsylvania.
SAGE Open Med Case Rep
November 2024
Division of Dermatology, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL, Canada.
Exposure to certain drugs can trigger new-onset psoriasis or flaring of existing psoriatic disease. The clinical presentation of drug-induced psoriasis can vary, and although there are features suggestive of drug-induced psoriasis, there are currently no standardized criteria to differentiate it from conventional psoriasis. Patients may present with localized psoriasiform plaques, or variants such as palmoplantar, nail disease, or widespread erythroderma.
View Article and Find Full Text PDFCancers (Basel)
October 2024
Oncologic Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Cureus
September 2024
Oncology, Biokliniki Athinon, Athens, GRC.
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