• 101 patients with HER2+ MBC on pertuzumab and trastuzumab were included. • Most observed cardiotoxicity were mild, all occurred early within 24 months. • Presence of cardiovascular co-morbidities predicts treatment cardiotoxicity. • Risk-stratified de-escalation of long-term cardiac surveillance should be discussed.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10921031PMC
http://dx.doi.org/10.1016/j.breast.2023.103612DOI Listing

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