AI Article Synopsis
- A 36-year-old man died from an infection with V. vulnificus after eating oysters at a restaurant, leading to septicaemia and organ failure.
- The bacteria was identified from his blood sample, showing it was susceptible to all tested antibiotics, while strains from oyster samples were collected but found to be distantly related.
- The study found that the specific strain from the patient was more virulent than strains from other sources, highlighting concerns about V. vulnificus contamination in seafood in the area.
Article Abstract
We report a 36-year-old male patient died of V. vulnificus-induced septicaemia and multiple organ failure syndrome after oyster consumption at a restaurant. We isolated and identified V. vulnificus vv16015 from the patient's blood sample and antibiotic susceptibility tests indicated sensitivity to all 21 antibiotics. Oyster samples were subsequently collected from the restaurant's supplier and three strains of V. vulnificus were isolated. Whole genome sequencing and analysis revealed vv16015 to be distantly related to these strains and confirmed that V. vulnificus contamination was present in the seafood of the restaurant and supplier. Using a Galleria mellonella larvae infection model, the virulence of vv16015 was determined to be higher than that of comparison strains isolated from a surviving patient (vv15018) and an oyster (vv220015). The human and environment distribution of V. vulnificus in Shenzhen is sporadic and heterogeneous, and vv16015 is highly virulent compared to other strains.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675978 | PMC |
| http://dx.doi.org/10.1186/s13099-023-00580-x | DOI Listing |
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