The purpose of this study is to develop a lightweight and easily deployable deep learning system for fully automated content-based brain MRI sorting and artifacts detection. 22092 MRI volumes from 4076 patients between 2017 and 2021 were involved in this retrospective study. The dataset mainly contains 4 common contrast (T1-weighted (T1w), contrast-enhanced T1-weighted (T1c), T2-weighted (T2w), fluid-attenuated inversion recovery (FLAIR)) in three perspectives (axial, coronal, and sagittal), and magnetic resonance angiography (MRA), as well as three typical artifacts (motion, aliasing, and metal artifacts). In the proposed architecture, a pre-trained EfficientNetB0 with the fully connected layers removed was used as the feature extractor and a multilayer perceptron (MLP) module with four hidden layers was used as the classifier. Precision, recall, F1_Score, accuracy, the number of trainable parameters, and float-point of operations (FLOPs) were calculated to evaluate the performance of the proposed model. The proposed model was also compared with four other existing CNN-based models in terms of classification performance and model size. The overall precision, recall, F1_Score, and accuracy of the proposed model were 0.983, 0.926, 0.950, and 0.991, respectively. The performance of the proposed model was outperformed the other four CNN-based models. The number of trainable parameters and FLOPs were the smallest among the investigated models. Our proposed model can accurately sort head MRI scans and identify artifacts with minimum computational resources and can be used as a tool to support big medical imaging data research and facilitate large-scale database management.
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http://dx.doi.org/10.1007/s10916-023-02017-z | DOI Listing |
Biogerontology
January 2025
Clinic for Heart Surgery (UMH), Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Straße 40, 06120, Halle (Saale), Germany.
If a shortened lifespan is evolutionarily advantageous, it becomes more likely that nature will strive to change it accordingly, affecting how we understand aging. Premature mortality because of aging would seem detrimental to the individual, but under what circumstances can it be of value? Based on a relative incremental increase in fitness, simulations were performed to reveal the benefit of death. This modification allows for continuous evolution in the model and establishes an optimal lifespan even under challenging conditions.
View Article and Find Full Text PDFJ Gastrointest Cancer
January 2025
Colorectal Research Center, Imam Khomeini Hospital complex, Tehran University of Medical Sciences, Keshavarz Blvd, Tehran, Iran.
Purpose: Carcinoembryonic antigen (CEA) is an important prognostic factor for rectal cancer. This study aims to introduce a novel cutoff point for CEA within the normal range to improve prognosis prediction and enhance patient stratification in rectal cancer patients.
Methods: A total of 316 patients with stages I to III rectal cancer who underwent surgical tumor resection were enrolled.
Brain Struct Funct
January 2025
Department of Biomedical Engineering, College of Chemistry and Life Sciences, Beijing University of Technology, Beijing, 100124, China.
The brain undergoes atrophy and cognitive decline with advancing age. The utilization of brain age prediction represents a pioneering methodology in the examination of brain aging. This study aims to develop a deep learning model with high predictive accuracy and interpretability for brain age prediction tasks.
View Article and Find Full Text PDFJ Chem Theory Comput
January 2025
Preferred Networks, Inc., Tokyo 100-0004, Japan.
Mapping the chemical reaction pathways and their corresponding activation barriers is a significant challenge in molecular simulation. Given the inherent complexities of 3D atomic geometries, even generating an initial guess of these paths can be difficult for humans. This paper presents an innovative approach that utilizes neural networks to generate initial guesses for reaction pathways based on the initial state and learning from a database of low-energy transition paths.
View Article and Find Full Text PDFAm J Hosp Palliat Care
January 2025
Division of Supportive and Palliative Care, National Cancer Centre Singapore, Singapore.
Background: In their care of terminally ill patients, palliative care physicians and oncologists are increasingly predisposed to physical and emotional exhaustion, or compassion fatigue (CF). Challenges faced by physicians include complex care needs; changing practice demands, and sociocultural contextual factors. Efforts to better understand CF have, however, been limited.
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