AI Article Synopsis
- Blackberries contain beneficial antioxidants and other substances, with new technologies being developed to improve their absorption in the body.
- Studies have assessed these substances' effectiveness using various models, including rodent ischemia models, typically with healthy foods being given beforehand to enhance their impact.
- Recent research involved pre-administering blackberry extracts to Mongolian gerbils in a hyperlipidemia model to study their effects before an ischemic event.
Article Abstract
Blackberries are abundant in substances that have antioxidative and other effects, and technologies for enhancing the effectiveness of their incorporation into the body are being developed. The effectiveness of such substances has been investigated in various models, including rodent ischemia models. While a test substance can be administered either before or after an event, healthy foods are generally pre-administered prophylactically in experiments. Pre-administration may have the potential to elevate the blood concentration of the active substance sufficiently prior to the event and/or induce adaptive changes in the ischemic tolerance of the recipient through long-term pre-administration. Based on the recently reported 2-week pre-administration of blackberries in a rat model, we investigated the pre-administration of blackberry extracts in a hyperlipidemia model using Mongolian gerbils. We then discussed the effects of the pre-administration on the treated animals before an ischemic event.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673227 | PMC |
| http://dx.doi.org/10.3390/metabo13111114 | DOI Listing |
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