AI Article Synopsis

  • Unilateral tonsillar enlargement is often a reason for tonsillectomy, but the risk of malignancy in asymmetrical tonsils is unclear and lacks standardized management guidelines.
  • A rare case of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) was reported in a 51-year-old man whose symptoms included tonsillar asymmetry and obstructive sleep apnea without typical signs of cancer.
  • This case emphasizes the need for careful physical examinations, considering family history, and obtaining tissue biopsies in patients with OSA and asymmetric tonsils to rule out rare malignancies.

Article Abstract

Unilateral tonsillar enlargement is a common indication for tonsillectomy, but there are varying rates of malignancy among tonsils removed for asymmetry and a lack of clear guidelines for management within the literature. Lymphoma of the palatine tonsils is among the concerns leading to tonsillectomy, but chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) of the tonsil is rare. We report a case of primary CLL/SLL of the palatine tonsil in a 51-year-old gentleman who presented with tonsillar asymmetry and obstructive sleep apnea (OSA) but lacked signs and symptoms suspicious for malignancy, including lymphadenopathy and "B-symptoms." To our knowledge, only 7 cases of CLL/SLL of the palatine tonsil have been reported in the English literature, with the tonsil being the primary site of involvement in only 4 of those cases. Our unique case highlights the importance of thorough physical exam, family history, and tissue biopsy in patients presenting to the otolaryngologist with OSA and asymmetric tonsils.

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http://dx.doi.org/10.1177/01455613231214634DOI Listing

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