Aims: The aim of this study is to measure staff compliance with the local umbilical cord lactate (UCL) sampling guideline and investigate the quality of paired UCG samples at a tertiary maternity unit.
Methods: We performed a retrospective consecutive sampling of 100 babies delivered via emergency caesarean section and 50 babies with each of all other guideline-based indications for UCL sampling born on and before 31 December 2021. Data were extracted from physical and electronic records. Compliance with guideline-based indications for UCL at birth was measured. The proportion of valid UCG samples was calculated. Samples were considered invalid under the following cases: (i) inadvertently collecting from the same vessel, (ii) switching arterial and venous samples, (iii) collecting from only one vessel or (iv) committing errors during sample collection and handling.
Results: Of the samples collected at birth from 321 babies, 280 (87%) had UCL. Small for gestational age and concerns about fetal well-being in labour were indications associated with poorer compliance, 66% and 78%, respectively. About 99 (44%) babies of 226 babies with UCG performed had valid UCG samples. The most common reasons for invalid samples were collection and handling errors (22%) and inadvertent collection from the same vessel (15%).
Conclusions: Generally, compliance with the guidelines is good. However, invalid UCG samples were more frequent than expected.
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http://dx.doi.org/10.1111/ajo.13770 | DOI Listing |
Rheumatology (Oxford)
January 2025
School of Management, Shanxi Medical University, Taiyuan, China.
Objectives: Rheumatoid arthritis (RA) is a chronic, destructive autoimmune disorder predominantly targeting the joints, with gut microbiota dysbiosis being intricately associated with its progression. The aim of the present study was to develop of effective early diagnostic methods for early RA based on gut microbiota.
Methods: A cohort comprising 262 RA patients and 475 healthy controls (HCs) was recruited.
Microorganisms
January 2025
University of Chinese Academy of Sciences, Beijing 101408, China.
The seasonal variations that occur in the gut microbiota of healthy adult rhesus monkeys kept in outdoor groups under conventional rearing patterns and how these variations are affected by environmental variables are relatively poorly understood. In this study, we collected 120 fecal samples from 30 adult male rhesus monkeys kept in outdoor groups across four seasons and recorded the temperature and humidity of the housing facilities, as well as the proportions of fruit and vegetables in their diet. A 16S rRNA sequencing analysis showed that the alpha diversity of the gut microbiota of the rhesus monkeys was higher in winter and spring than in summer and autumn.
View Article and Find Full Text PDFDent J (Basel)
January 2025
Institute of Dentistry, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
: Halitosis is primarily caused by the activity of oral microorganisms. In this study, we employed metagenomic sequencing and metabolomic approaches to investigate the differences in salivary microbiota and metabolite profiles between individuals with halitosis and periodontitis and healthy controls. Additionally, we expanded the study to examine how oral malodorous compounds interact with human oral squamous carcinoma (HSC-4) cells.
View Article and Find Full Text PDFACS Omega
January 2025
State Key Laboratory of Petroleum Resources and Engineering, China University of Petroleum, Beijing 102249, China.
Under the environment of energy transformation in the world, underground coal gasification (UCG) is an important means to realize the green and clean development and utilization of deep coal resources. Due to a series of complex chemical reactions, the porosity and permeability of coal have changed significantly. Accurately characterizing the porosity and permeability of gasified coal is of great significance to the field screening, production control, and numerical simulation of the UCG project.
View Article and Find Full Text PDFAging Dis
January 2025
Institute of Nutrition and Food Technology (INTA), Universidad de Chile, Santiago, Chile.
The gut-brain axis is a bidirectional communication pathway that modulates cognitive function. A dysfunctional gut-brain axis has been associated with cognitive impairments during aging. Therefore, we propose evaluating whether modulation of the gut microbiota through fecal microbiota transplantation (FMT) from young-trained donors (YT) to middle-aged or aged mice could enhance brain function and cognition in old age.
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