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A Trespasser in Lymph Node: A Case Report.
Cureus
September 2024
Pathology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Cryptococcal meningitis is a prevalent, opportunistic fungal disease seen in human immunodeficiency virus (HIV)-infected individuals. A lymph node is an unusual presentation site for and can mimic tuberculosis. Disseminated cryptococcosis is a life-threatening disease that is seen commonly in acquired immunodeficiency syndrome (AIDS).
View Article and Find Full Text PDFDisseminated cryptococcosis in a child with liver transplantation: a case report.
Turk J Pediatr
October 2024
Division of Gastroenterology, Hepatology and Nutrition Disease, Department of Pediatrics, Medical School of Ege University, İzmir, Türkiye.
Background: Cryptococcus neoformans causes cryptococcosis, primarily affecting immunocompromised individuals, including solid-organ transplant recipients, and, less frequently, immunocompetent people.
Case: A 15-year-old male with congenital hepatic fibrosis, portal hypertension, and cirrhosis underwent orthotopic liver transplantation. He received perioperative antimicrobial and antifungal prophylaxis and continued immunosuppressive treatment.
Successful treatment of disseminated cryptococcosis with liposomal amphotericin B and isavuconazole in an adult living with HIV: A case report and literature review.
J Infect Chemother
October 2024
Division of Respirology, Rheumatology, Infectious Diseases, and Neurology, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan. Electronic address:
Article Synopsis
- Treating cryptococcosis in HIV patients is tough due to limited antifungal options and lack of approval for isavuconazole in the US and Europe.
- A case study follows a Japanese man who developed cryptococcal meningitis, relapsed after fluconazole treatment, and was later diagnosed with disseminated cryptococcosis.
- He was successfully treated with a combination of isavuconazole and liposomal amphotericin B, suggesting that isavuconazole may be a viable treatment option, warranting further clinical trials to ensure effectiveness and safety.*
Cryptococcus Neoformans Osteomyelitis of the Right Ankle Diagnosed by Metagenomic Next-Generation Sequencing in a HIV-Negative Patient with Tuberculous Lymphadenitis and Pulmonary Tuberculosis: A Case Report and Recent Literature Review.
Infect Drug Resist
September 2024
Department of Tuberculosis, Hangzhou Red Cross Hospital, Hangzhou, People's Republic of China.
Article Synopsis
- This text discusses a rare case of cryptococcal osteomyelitis in a 67-year-old woman, complicated by tuberculosis, that was challenging to diagnose due to its similarity to other lung infections.
- Metagenomic Next-Generation Sequencing (mNGS) was used to accurately identify the infection after a biopsy, confirming the presence of Cryptococcus neoformans through additional tests.
- The case highlights the importance of advanced genomic techniques in diagnosing complex infections and shows that cryptococcal osteomyelitis, while rare, can be effectively treated with surgery and antifungal medication.
Cryptococcal Lymphadenitis.
Arch Bronconeumol
January 2024
Department of Radiology, The First Affiliate Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, Hunan Province, China. Electronic address:
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