Navigating the challenges of data-driven speech processing, one of the primary hurdles is accessing reliable pathological speech data. While public datasets appear to offer solutions, they come with inherent risks of potential unintended exposure of patient health information via re-identification attacks. Using a comprehensive real-world pathological speech corpus, with over n[Formula: see text]3800 test subjects spanning various age groups and speech disorders, we employed a deep-learning-driven automatic speaker verification (ASV) approach. This resulted in a notable mean equal error rate (EER) of [Formula: see text], outstripping traditional benchmarks. Our comprehensive assessments demonstrate that pathological speech overall faces heightened privacy breach risks compared to healthy speech. Specifically, adults with dysphonia are at heightened re-identification risks, whereas conditions like dysarthria yield results comparable to those of healthy speakers. Crucially, speech intelligibility does not influence the ASV system's performance metrics. In pediatric cases, particularly those with cleft lip and palate, the recording environment plays a decisive role in re-identification. Merging data across pathological types led to a marked EER decrease, suggesting the potential benefits of pathological diversity in ASV, accompanied by a logarithmic boost in ASV effectiveness. In essence, this research sheds light on the dynamics between pathological speech and speaker verification, emphasizing its crucial role in safeguarding patient confidentiality in our increasingly digitized healthcare era.
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http://dx.doi.org/10.1038/s41598-023-47711-7 | DOI Listing |
Healthcare (Basel)
December 2024
Department of Speech Therapy, School of Health Sciences, University of Ioannina, 455 00 Ioannina, Greece.
This study presents a comprehensive investigation into the correlation between Rare Diseases and Syndromes (RDS) and the dysphagic disorders manifested during childhood and adulthood in affected patients. Dysphagia is characterized by difficulty or an inability to swallow food of any consistency, as well as saliva or medications, from the oral cavity to the stomach. RDS often present with complex and heterogeneous clinical manifestations, making it challenging to develop standardized diagnostic and therapeutic approaches.
View Article and Find Full Text PDFMol Med Rep
March 2025
Department of Pathology, Aretaieion University Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Intrauterine growth restriction (IUGR) is the second most common obstetric complication after preterm labor. Appropriate trophoblast differentiation and placental structure, growth and function are key for the maintenance of pregnancy and normal fetal growth, development and survival. Extravillous trophoblast cell proliferation, migration and invasion are regulated by molecules produced by the fetomaternal interface, including autocrine factors produced by the trophoblast, such as insulin‑like growth factor (IGF)‑1.
View Article and Find Full Text PDFCureus
December 2024
Neurosurgery, Southmead Hospital, North Bristol NHS, Bristol, GBR.
Cerebral arteriovenous malformations (AVMs) are tangles of abnormal vessels with early arteriovenous (AV) shunting that can lead to intracerebral hemorrhage, seizures, neurologic deficit, or headache. To date, only a few cases of carcinomas metastasizing to pre-existing cerebral AVMs have been reported in the literature. However, renal clear cell carcinoma (RCC) brain metastases that exhibit early AV shunting, where AVM pathology is not present, are extremely rare.
View Article and Find Full Text PDFActa Otolaryngol
January 2025
Department of Otorhinolaryngology Head and Neck Surgery, Tianjin First Central Hospital, Tianjin, China.
Background: The early diagnosis of glottic laryngeal cancer is the key to successful treatment, and machine learning (ML) combined with narrow-band imaging (NBI) laryngoscopy provides a new idea for the early diagnosis of glottic laryngeal cancer.
Objective: To explore the clinical applicability of the diagnosis of early glottic cancer based on ML combined with NBI.
Material And Methods: A retrospective study was conducted on 200 patients diagnosed with laryngeal mass, and the general clinical characteristics and pathological results of the patients were collected.
Int J Speech Lang Pathol
January 2025
Faculty of Medicine and Health Sciences, University of East Anglia, Norwich, UK.
Purpose: This study aims to explore the current practices and challenges faced by speech-language pathologists in three Southeast Asian countries (Malaysia, Indonesia, and Vietnam) in assessing and treating multilingual children with developmental language disorder.
Method: A survey was designed and administered to 110 speech-language pathologists across Malaysia, Indonesia, and Vietnam. The survey contained 60 questions on current practices and knowledge of existing resources for assessing and treating multilingual children with developmental language disorder.
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