This study evaluated the efficacy of dialectical behaviour group therapy (GPT) vs. individual clinical management (CM) and methylphenidate (MPH) vs. placebo (PLB) on emotional symptoms in adults with ADHD. This longitudinal multicentre RCT compared four groups (GPT+MPH, GPT+PLB, CM+MPH, and CM+PLB) over five assessment periods, from baseline to week 130. Emotional symptomatology was assessed using SCL-90-R subscales. Of the 433 randomised participants, 371 remained for final analysis. At week 13, the GPT+MPH group showed smaller reductions in anxiety symptoms than the CM groups, but the differences disappeared at subsequent assessments. Improvements in emotional symptom were significantly predicted by reductions in core ADHD symptoms in all groups except the GPT+MPH group. The unexpected lack of between-group differences may be explained by a "floor effect", different intervention settings (group vs. individual), and psychotherapy type. Multiple regression analyses suggest a more specific effect of combined interventions (GPT+MPH). Implications for clinical practice are discussed. Clinical trial registration: ISRCTN54096201 (Current Controlled Trials).
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http://dx.doi.org/10.1016/j.psychres.2023.115610 | DOI Listing |
Psychooncology
January 2025
Department of Social Sciences and Health Policy, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.
Objective: Novel behavioral interventions are needed for patients with cancer who smoke cigarettes. Standard tobacco treatment may not effectively address the psychological distress and/or emotion dysregulation that makes quitting smoking difficult for many patients. Dialectical Behavior Therapy-Skills Training (DBT-ST) has demonstrated efficacy as a brief intervention for managing emotions and stress across varied populations but has not been adapted for patients with cancer who smoke.
View Article and Find Full Text PDFChildren (Basel)
November 2024
School of Rural Health, Monash University, Melbourne, VIC 3800, Australia.
Mental health concerns among youth represent a critical global public health issue. Research has found that youth with mental health concerns are often reliant on their caregivers while being isolated from peers. Guided by the recovery model of mental health care, this study investigates the often-overlooked role of caregivers in fostering 'connectedness' in youth; Methods: Semi-structured interviews were conducted with nine caregivers of youth with mental health issue; Results: Thematic analysis underscored three tasks in the role of caregivers in promoting connectedness in youth: (a) understanding the nature and quality of social networks, (b) supporting readiness to engage in social relationships, and (c) promoting their youth's social problem solving and self-efficacy; Discussion: These tasks highlight the complex dialectics faced by caregivers in supporting youth recovery.
View Article and Find Full Text PDFCancer
January 2025
Stephenson Cancer Center, University of Oklahoma Health Sciences Center/Sarah Cannon Research Institute, Oklahoma City, Oklahoma, USA.
Background: Yttrium-90 FF-21101 (Y-FF-21101) is a radiopharmaceutical that targets P-cadherin as a therapy against solid tumors. A previously reported, first-in-human study determined that a dose of 25 mCi/m was safe, and a patient with clear cell carcinoma of the ovary achieved a complete response. In this article, the authors report the results of Y-FF-21101 treatment in an ovarian carcinoma expansion cohort and in patients with selected solid tumors who had known high P-cadherin expression.
View Article and Find Full Text PDFFront Psychol
December 2024
School of Mental Health and Psychological Science, Anhui Medical University, Hefei, China.
Background: Medical students are confronted with a complex stress environment, encompassing academic challenges, residency training, and future workplace pressures. Therefore, the exploration of effective psychological capital intervention strategies is crucial for enhancing their mental health and promoting career development.
Objective: The aim of this study was to evaluate the efficacy of group cognitive-behavioral therapy (GCBT) and dialectical behavior therapy (DBT) in boosting the psychological capital of medical students and to compare the advantages and disadvantages of these two therapies.
Psychol Med
December 2024
SEED Lifespan Strategic Research Centre, School of Psychology, Faculty of Health, Deakin University, Geelong, Australia.
Background: Dialectical behavior therapy (DBT) is a specialized treatment that has a growing evidence base for binge-spectrum eating disorders. However, cost and workforce capacity limit wide-scale uptake of DBT since it involves over 20 in-person sessions with a trained professional (and six sessions for guided self-help format). Interventions translated for delivery through modern technology offer a solution to increase the accessibility of evidence-based treatments.
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