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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656173 | PMC |
http://dx.doi.org/10.5826/dpc.1304a218 | DOI Listing |
Dermatol Pract Concept
October 2023
Department of Dermatology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Ann Allergy
July 1992
Istituto di Clinica Medica, Università Cattolica del S. Cuore, Rome, Italy.
We report two cases of cutaneous adverse reactions during treatment with diltiazem. Both patients developed wide-spread, pruriginous, erythematous, maculopapular eruptions with fever and facial angioedema, 48 to 72 hours after starting diltiazem. Delayed hypersensitivity to diltiazem was suspected and the diagnosis was confirmed by skin patch tests followed by cutaneous biopsy.
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