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http://dx.doi.org/10.1097/CORR.0000000000002932 | DOI Listing |
JACC Heart Fail
January 2025
Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Data from large-scale, randomized, controlled trials demonstrate that contemporary treatments for heart failure (HF) can substantially improve morbidity and mortality. Despite this, observed outcomes for patients living with HF are poor, and they have not improved over time. The are many potential reasons for this important problem, but inadequate use of optimal medical therapy for patients with HF, an important component of guideline-directed medical therapy, in routine practice is a principal and modifiable contributor.
View Article and Find Full Text PDFNucleic Acids Res
January 2025
Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius, 10257, Lithuania.
The expansion of single-cell analytical techniques has empowered the exploration of diverse biological questions at the individual cells. Droplet-based single-cell RNA sequencing (scRNA-seq) methods have been particularly widely used due to their high-throughput capabilities and small reaction volumes. While commercial systems have contributed to the widespread adoption of droplet-based scRNA-seq, their relatively high cost limits the ability to profile large numbers of cells and samples.
View Article and Find Full Text PDFAdv Mater
January 2025
Materdicine Lab, School of Life Sciences, Shanghai University, Shanghai, 200444, China.
Cancer immunotherapy, which leverages immune system components to treat malignancies, has emerged as a cornerstone of contemporary therapeutic strategies. Yet, critical concerns about the efficacy and safety of cancer immunotherapies remain formidable. Nanotechnology, especially polymeric nanoparticles (PNPs), offers unparalleled flexibility in manipulation-from the chemical composition and physical properties to the precision control of nanoassemblies.
View Article and Find Full Text PDFJ Clin Med
December 2024
Dental Unit, Department of Surgical Sciences (DISC), University of Genoa, 16132 Genova, Italy.
The aim of this study was to systematically revise the state of art of the accuracy of digital and conventional impressions in clinical full-arch scenarios. Electronic and manual searches were conducted up to December 2024. Only trials comparing the accuracy of digital versus conventional impressions were selected by two independent reviewers.
View Article and Find Full Text PDFSensors (Basel)
January 2025
Institute of Intelligent Manufacturing Technology, Shenzhen Polytechnic University, Shenzhen 518000, China.
This paper introduces a novel energy-efficient lightweight, void hole avoidance, localization, and trust-based scheme, termed as Energy-Efficient and Trust-based Autonomous Underwater Vehicle (EETAUV) protocol designed for 6G-enabled underwater acoustic sensor networks (UASNs). The proposed scheme addresses key challenges in UASNs, such as energy consumption, network stability, and data security. It integrates a trust management framework that enhances communication security through node identification and verification mechanisms utilizing normal and phantom nodes.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!