The relationship between 433 V. cholerae strains and 571 enterobacterial strains, isolated from different ecosystems, have been studied by the method of "delayed antagonism". The direct correlation between the virulence of V. cholerae and the width of the spectra of their antagonistic activity towards indicator bacteria was detected. The expediency of studies on the role of the vibriocinogenic factor in the survival of V. cholerae in different ecological systems is substantiated.

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