AI Article Synopsis
- - We conducted whole-exome sequencing to study genetic factors that may contribute to patent ductus arteriosus in Japanese macaques.
- - By comparing our findings with the reference sequences of other primates, we found potential missense variants in five specific genes.
- - The identified genes include ADAM15, AZGP1, CSPG4, TNFRSF13B, and EPOR, which may play a role in this condition.
Article Abstract
We performed whole-exome sequencing using a human exome capture kit to analyze the potential genetic factors related to patent ductus arteriosus in Japanese macaques. Compared with the reference sequences of other primates, we identified potential missense variants in five genes: ADAM15, AZGP1, CSPG4, TNFRSF13B, and EPOR.
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| http://dx.doi.org/10.1111/jmp.12686 | DOI Listing |
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