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http://dx.doi.org/10.1007/s12630-023-02658-1 | DOI Listing |
Support Care Cancer
October 2024
Department of Medicine, Oncology Unit, "SS Antonio E Biagio E C. Arrigo" Hospital, 15121, Alessandria, Italy.
J Bone Miner Res
November 2024
Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, 1825 University Blvd., Birmingham, AL 35294, United States.
J Bone Miner Res
November 2024
Menzies Institute for Medical Research and Faculty of Health, University of Tasmania, Hobart, Tasmania 7000, Australia.
Front Endocrinol (Lausanne)
January 2024
Instituto de Investigación Biosanitaria de Granada, Granada, Spain.
Introduction: Hypophosphatasia (HPP) is an inborn metabolic error caused by mutations in the ALPL gene encoding tissue non-specific alkaline phosphatase (TNSALP) and leading to decreased alkaline phosphatase (ALP) activity. Although the main characteristic of this disease is bone involvement, it presents a great genetic and clinical variability, which makes it a systemic disease.
Methods: Patients were recruited based on biochemical assessments.
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