Flaxseed has been recognized as a valuable source of nutrients and bioactive compounds, including proteins that possess various health benefits. In recent years, studies have shown that flaxseed proteins, including albumins, globulins, glutelin, and prolamins, possess anti-cancer properties. These properties are attributed to their ability to inhibit cancer cell proliferation, induce apoptosis, and interfere with cancer cell signaling pathways, ultimately leading to the inhibition of metastasis. Moreover, flaxseed proteins have been reported to modulate cancer cell mechanobiology, leading to changes in cell behavior and reduced cancer cell migration and invasion. This review provides an overview of the anti-cancer properties of flaxseed proteins, with a focus on their potential use in cancer treatment. Additionally, it highlights the need for further research to fully establish the potential of flaxseed proteins in cancer therapy.
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http://dx.doi.org/10.3390/proteomes11040037 | DOI Listing |
Physiol Mol Biol Plants
December 2024
Science and Technology Department, University College in Nairiyah, University of Hafr Al Batin (UHB), 31991 Nairiyah, Saudi Arabia.
Salinity is one of the abiotic stress factors that affect plant physiology and cause various plant disorders. Thiourea, which consists of amino, thiol, and imino groups, is an antioxidant and growth regulator. The objective was to determine the antioxidant role of thiourea (0, 3, 6 mM) in attenuating the effects of salinity (0 mM, 50 mM, 100 mM NaCl) on growth, yield, and some biochemical compositions of flax ( L.
View Article and Find Full Text PDFNucleic Acids Res
December 2024
Friedrich Schiller University, Institute of Microbiology, 07743 Jena, Germany.
Gene regulation at the post-transcriptional level is prevalent in all domains of life. In bacteria, ProQ-like proteins have emerged as important RNA chaperones facilitating RNA stability and RNA duplex formation. In the major human pathogen Vibrio cholerae, post-transcriptional gene regulation is key for virulence, biofilm formation, and antibiotic resistance, yet the role of ProQ has not been studied.
View Article and Find Full Text PDFMol Nutr Food Res
December 2024
Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada.
The objective of this omega-3 feeding study was to elucidate the independent effects of α-linolenic acid (ALA) versus eicosapentaenoic (EPA)/docosahexaenoic acid (DHA) on visceral adiposity and inflammatory signaling in diet-induced obese delta-6 desaturase (Fads2) knockout (KO) mice. Male wildtype (WT) and Fads2 KO mice were fed a high-fat diet (45% kcal from fat) containing either lard (no omega-3s), flaxseed (ALA), or menhaden (EPA/DHA) for 21 weeks. Epididymal white adipose tissue (eWAT) was analyzed for changes in tissue weight, adipocyte size, triacylglycerol (TAG) and fatty acid content, and inflammatory markers.
View Article and Find Full Text PDFBMC Biotechnol
December 2024
Institute of Food Biotechnology and Genomics of National Academy of Sciences of Ukraine, 2a Baidy-Vyshnevetskoho str., Kyiv, 04123, Ukraine.
Background: False flax, or gold-of-pleasure (Camelina sativa) is an oilseed that has received renewed research interest as a promising vegetable oil feedstock for liquid biofuel production and other non-food uses. This species has also emerged as a model for oilseed biotechnology research that aims to enhance seed oil content and fatty acid quality. To date, a number of genetic engineering and gene editing studies on C.
View Article and Find Full Text PDFNutrients
November 2024
Department of Exercise and Health Promotion, College of Kinesiology and Health, Chinese Culture University, Taipei 111396, Taiwan.
Effective post-exercise recovery is vital for optimizing athletic performance, focusing on muscle repair, glycogen replenishment, rehydration, and inflammation management. This review explores the evolving trend from traditional supplements, such as protein, carbohydrates, creatine, and branched-chain amino acids (BCAAs), toward functional foods rich in bioactive compounds. Evidence highlights the benefits of functional foods like tart cherry juice (anthocyanins), turmeric-seasoned foods, and sources of omega-3 fatty acids, including fish, flaxseeds, chia seeds, and walnuts, for mitigating oxidative stress and inflammation.
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