AI Article Synopsis
- Pancreatic cancer is aggressive and usually spreads, but bone metastases are rare; this report highlights a case of successful long-term survival following the surgical removal of such a metastasis.
- A 60-year-old woman underwent surgery for pancreatic cancer and developed lung metastases, which disappeared after chemotherapy; then, a bone metastasis was found 77 months later.
- The patient underwent thoracoscopic surgery to remove the bone metastasis after successful chemotherapy, and she remains cancer-free 44 months post-surgery, suggesting that surgical options may be viable for well-controlled cases.
Article Abstract
Introduction: Pancreatic cancer (PC) is highly malignant and metastatic; however, bone metastases are rare. Although the effectiveness of conversion surgery for distant metastases of PC has been reported in a few cases, there are no reports on surgical resection for bone metastases. Here, we report a case of long-term survival after resection of bone metastasis from PC.
Patient Concerns: A 60-year-old woman underwent pancreaticoduodenectomy after neoadjuvant chemoradiotherapy for pancreatic head cancer. At 28 months after surgery, multiple lung metastases from PC were diagnosed, and chemotherapy was administered. After 59 months, chemotherapy was terminated because all target lesions had disappeared on imaging.
Diagnosis: At 77 months after the initial surgery, bone metastasis in the left 9th rib was detected by positron emission tomography/computed tomography, which was performed due to elevated carbohydrate antigen 19-9 levels.
Interventions: Chemotherapy was readministered as the initial treatment. Subsequently, due to the long-term well-controlled status of the recurrence site and the absence of other metastases, thoracoscopic-assisted partial resection of the left 9th rib was performed 128 months following pancreaticoduodenectomy. Pathological examination revealed adenocarcinoma metastasis from PC.
Outcomes: The patient is currently alive without recurrence 44 months after resection for bone metastasis and 172 months after the initial surgery.
Conclusion: Surgical resection may be favorable in patients with bone metastasis of PC that is well-controlled with chemotherapy.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659668 | PMC |
| http://dx.doi.org/10.1097/MD.0000000000035856 | DOI Listing |
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