Unusual False Positive on Tc-Tektrotyd Scintigraphy Mimicking Bone Metastasis.

Nucl Med Mol Imaging

Nuclear Medicine Department, Mohammed VI University Hospital, Cadi Ayyad University, Marrakech, Morocco.

Published: December 2023

Somatostatin receptor scintigraphy is a key diagnostic tool in the initial staging and therapeutic evaluation of neuroendocrine tumors. Its specificity can be compromised by the presence of false positives. We illustrate here the case of a vertebral hemangioma detected on Tc-Tektrotyd scintigraphy as an incidental finding in a 34-year-old man referred for the staging of a well-differentiated neuroendocrine tumor of the ampulla of Vater (Fig. 1).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654281PMC
http://dx.doi.org/10.1007/s13139-023-00803-8DOI Listing

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Article Synopsis
  • - Optic nerve sheath meningiomas are rare tumors that can lead to vision loss, making accurate diagnosis challenging, especially since confirming their presence often requires risky procedures.
  • - Current diagnostic methods primarily include CT and MRI, but these imaging techniques may not always yield a clear diagnosis, prompting the need for other alternatives.
  • - This case study highlights the successful use of a [99mTc]Tc-Tektrotyd SPECT/CT scan as a non-invasive method for diagnosing orbital tumors, leveraging the radiopharmaceutical's ability to bind to somatostatin receptor subtype 2 found in meningiomas.
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Unusual False Positive on Tc-Tektrotyd Scintigraphy Mimicking Bone Metastasis.

Nucl Med Mol Imaging

December 2023

Nuclear Medicine Department, Mohammed VI University Hospital, Cadi Ayyad University, Marrakech, Morocco.

Somatostatin receptor scintigraphy is a key diagnostic tool in the initial staging and therapeutic evaluation of neuroendocrine tumors. Its specificity can be compromised by the presence of false positives. We illustrate here the case of a vertebral hemangioma detected on Tc-Tektrotyd scintigraphy as an incidental finding in a 34-year-old man referred for the staging of a well-differentiated neuroendocrine tumor of the ampulla of Vater (Fig.

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Potential utility of SPECT/CT with 99mTc-Tektrotyd for imaging of post-myocardial infarction inflammation.

J Nucl Cardiol

December 2023

Cardiac Emergency Department, Cardiology Research Institute, Tomsk National Research Medical Centre, Russian Academy of Sciences, Tomsk, Russian Federation.

Background: There is a need to develop methods for post-myocardial infarction (MI) inflammation monitoring. Scintigraphy with somatostatin receptor targeted radiotracers has potential in this field. The purpose was to study the association of Tc-Tektrotyd uptake intensity in MI area with heart contractility indices over 6-month follow-up.

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Somatostatin receptor scintigraphy with 99m Tc-Tektrotyd is widely used for the investigation of neuroendocrine tumors. Overexpression of somatostatin receptors has been shown in different tumor types including lymphomas, breast carcinoma, and renal cell carcinoma (RCC). Isolated case reports have shown that RCC metastases can be identified using somatostatin receptor imaging such as Octreoscan scintigraphy and 68 Ga-DOTATATE PET/CT.

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Introduction: The aim was to assess the diagnostic value of Tc-Tektrotyd scintigraphy (TCT) and positron emission tomography/computed tomography using F-18 fluorodeoxyglucose (F-FDG PET/CT) in the detection and follow-up of neuroendocrine tumors (NETs), and their predictive value for disease progression.

Material And Methods: In this retrospective cohort, TCT and F-FDG PET/CT were performed in 90 patients (37 men, 53 women, mean age 52.7 ±15.

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