Beta-lactam, aminoglycoside, and quinolone resistance in strains isolated from shrimps and mussels in the Marmara Sea.

The purpose of the study was to examine the prevalence of  in shrimps and mussels, and to determine the distribution of β-lactam, aminoglycoside, quinolone, and multi-drug resistance phenotypically and genotypically in  isolates obtained from mussels and shrimps in Istanbul. Faecal samples were collected from mussels ( = 96) and shrimps ( = 96) from the Marmara Sea coastline and fish markets in Istanbul. For the detection of antibiotic susceptibilities, seven antibiotic groups were used. β-lactamase, aminoglycoside, and quinolone genes were also determined. A total of 34 (17.7%, 15 shrimps, and 19 mussels) were isolated, and 17 (50%) were found to be resistant to one or more antimicrobials. The highest resistance was seen against aminoglycosides with 11 isolates (32.35%), followed by quinolones with 10 isolates (29.41%) and extended-spectrum β-lactamase (ESBL) with 4 isolates (11.76%). Multi-drug resistance was detected in 5 isolates (14.7%) from 3 shrimp and 2 mussel samples. The prevalence of ESBL genes was demonstrated at 3.84% in mussels and shrimp samples. There were no AmpC and carbapenemase-producing genes. These samples harbored ( = 3) and ( = 4). Ten isolates were resistant to aminoglycosides genotypically. Resistance genes detected were in 2 isolates, in 5, and together in 3, ANT('')-Ia, and simultaneously in 3, in 1, in 1 isolate. gene was detected in only one of 10 phenotypically resistant isolates to quinolones.