AI Article Synopsis
- Two cases of Guillain-Barré syndrome (GBS) were initially misdiagnosed as lumbar spinal stenosis (LSS) based on observed weakness and MRI findings.
- Further neurological tests revealed upper extremity abnormalities, leading to suspicions of GBS, which were confirmed through specific antibody tests and positive response to treatment.
- The authors speculate that existing LSS may have disrupted the blood-nerve barrier, contributing to the unusual segmental weakness seen in these GBS cases.
Article Abstract
We herein report two cases of Guillain-Barré syndrome (GBS) mimicking lumbar spinal stenosis (LSS). Both cases were initially diagnosed as LSS based on prominent segmental weakness in the L5 and S1 myotomes and coexisting LSS on magnetic resonance imaging. However, neurological and electrophysiological examinations revealed abnormalities that extended to the upper extremities, although slight, prompting us to suspect GBS. Subsequently, serum antiganglioside antibodies and remarkable responsiveness to intravenous immunoglobulin therapy confirmed GBS. We suspect that the focal blood-nerve barrier disruption due to preexisting LSS might have contributed to the segmental weakness in this atypical GBS case.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11309858 | PMC |
| http://dx.doi.org/10.2169/internalmedicine.2875-23 | DOI Listing |
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