AI Article Synopsis

  • An unusual case of nephrotic syndrome following multiple bee and wasp stings in a 79-year-old woman is reported, leading to the diagnosis of membranous nephropathy.
  • After being stung seven times, the patient experienced significant weight gain, edema, and specific urine and serum test results indicative of nephrotic syndrome.
  • A kidney biopsy confirmed stage I membranous nephropathy, and the patient's condition improved with treatment, marking this as the first documented instance linking Hymenoptera stings to this type of kidney disease.

Article Abstract

An association between Hymenoptera (bee and wasp) stings and nephrotic syndrome has been rarely reported. We report a case of nephrotic syndrome after multiple Hymenoptera stings, and membranous nephropathy was later diagnosed by a kidney biopsy. The patient was a 79-year-old woman who was stung by Hymenoptera at seven sites on her body. A weight gain of 3.7 kg was observed in the patient at 1 week after being stung, and she had considerable edema in both lower extremities. A urine protein concentration of 14.8 g/g creatinine and a serum albumin concentration of 1.7 g/dL led to the diagnosis of nephrotic syndrome. A percutaneous kidney biopsy 8 days after the Hymenoptera stings showed stage I membranous nephropathy. She was in complete remission 1 week after the administration of oral prednisolone 40 mg/day, which was started 14 days after Hymenoptera stings, and had no relapse of nephrotic syndrome. To the best of our knowledge, this is the first report of biopsy-proven membranous nephropathy caused by Hymenoptera stings.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11144171PMC
http://dx.doi.org/10.1007/s13730-023-00834-2DOI Listing

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