In order to improve the detection accuracy of vertical barrier leakage, three contamination leakage working conditions, including point leakage only, point and vertical leakage, and horizontal leakage, were simulated by small-scale soil tank tests. The dynamic evolution of soil resistivity over time was monitored by electrical resistivity tomography (ERT). The accuracy of the ERT detection results was validated through thermal tracer method, chloride tracer method, and soil true resistivity experiments. The results indicate that the resistivity profiles at different times can more accurately reflect information on the location of leakage points, the extent of contamination plumes, and the migration pathways of pollutants under different working conditions. The extent of anomalous areas in resistivity profiles is a crucial factor in representing the geometric shape of pollution leakage. However, the preferential seepage or lateral migration of contaminant in the soil significantly reduces the detection accuracy of ERT for identifying leakage points. The thermal tracer method and the chloride tracer method can produce better complementary interpretations of ERT monitoring results. The measurement points near the leakage point exhibit faster temperature response rates, which can serve as a characteristic for identifying the location of leakage points. Compared with the thermal tracer method, the chloride tracer method can monitor the migration of contaminants over a larger range. Therefore, the proposed combined diagnostic detection method in this paper presents a feasible solution with promising engineering applications in leakage detection for vertical barrier barriers.
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http://dx.doi.org/10.1007/s11356-023-30958-y | DOI Listing |
Sci Rep
January 2025
Department of Neurosurgery of the Second Affiliated Hospital, Interdisciplinary Institute of Neuroscience and Technology, School of Medicine, Zhejiang University, Hangzhou, China.
Horizontal connections in anterior inferior temporal cortex (ITC) are thought to play an important role in object recognition by integrating information across spatially separated functional columns, but their functional organization remains unclear. Using a combination of optical imaging, electrophysiological recording, and anatomical tracing, we investigated the relationship between stimulus-response maps and patterns of horizontal axon terminals in the macaque ITC. In contrast to the "like-to-like" connectivity observed in the early visual cortex, we found that horizontal axons in ITC do not preferentially connect sites with similar object selectivity.
View Article and Find Full Text PDFBackground: Deficiency in the lysosomal enzyme, glucocerebrosidase (GCase), caused by mutations in the GBA1 gene, is the most common genetic risk factor for Parkinson's disease (PD). However, the consequence of reduced enzyme activity within neural cell sub-types remains ambiguous. Thus, the purpose of this study was to define the effect of GCase deficiency specifically in human astrocytes and test their non-cell autonomous influence upon dopaminergic neurons in a midbrain organoid model of PD.
View Article and Find Full Text PDFMater Today Bio
February 2025
Department of Nuclear Medicine, Gansu Provincial Cancer Hospital, Lanzhou, Gansu, 730050, China.
Liposomal nanocarriers are able to carry peptides for efficient and selective delivery of radioactive tracer and drugs into the tumors. Angiopoietin 2 (ANGPT2) is an excellent biomarker for precise diagnosis and therapy of glioma. The present study aimed to design ANGPT2-specific peptides to modify the surface of nanoliposomes containing doxorubicin (Dox) for integrative imaging and targeting therapy of glioma.
View Article and Find Full Text PDFAcad Radiol
January 2025
Department of Radiology, Washington University School of Medicine, 510 S. Kingshighway Blvd, St. Louis, MO 63110 (S.I., M.A.T., M.I., C.S., R.L., A.H., R.L.W., T.J.F.). Electronic address:
Rationale And Objective: Conventional positron emission tomography (PET) respiratory gating utilizes a fraction of acquired PET counts (i.e., optimal gate [OG]), whereas elastic motion correction with deblurring (EMCD) utilizes all PET counts to reconstruct motion-corrected images without increasing image noise.
View Article and Find Full Text PDFAppl Radiat Isot
January 2025
Service de Protection Radiologique des Armées, 1bis rue du Lieutenant Raoul Batany, 92141, Clamart cedex, France.
A specific goal of the French army is to ensure health protection of soldiers consuming water from overseas operations territories. To do so, the French Defence Radiological Protection Service developed a method to quantify the amount of Ra in water using Ra-Nucfilm discs. Ra analysis is achieved within less than two days and the detection limit, function of adsorption efficiency, ranges from 0.
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