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Could Madelung disease be a cause of stroke? A rare case report.
Folia Med (Plovdiv)
August 2024
Ankara Training and Research Hospital, Ankara, Turkiye.
Article Synopsis
- Multiple symmetric lipomatosis (MLS) is a rare metabolic disorder that leads to abnormal fat deposits.
- * It is also referred to as Launois-Bensaude syndrome or Madelung disease.
- * The condition is marked by symmetrical and non-encapsulated fat accumulations in various areas of the body.
A case report on Madelung's disease and comprehensive review of the literature.
Orphanet J Rare Dis
August 2024
Department of General surgery, Bethune International Peace Hospital, No. 398, Zhongshan West Road, Qiaoxi District, Shijiazhuang, 050051, Hebei Province, China.
Background: Madelung's disease (MD), alternatively referred to as benign symmetric lipomatosis, multiple symmetric lipomatosis, or Launois-Bensaude syndrome, is an uncommon benign disorder marked by symmetric proliferation of adipose tissue in the head, neck, and torso regions.
Case Description: In this case, the patient was a female with the late middle-aged demographic, diagnosed with Type I MD. Notably, she exhibited no prior history of alcohol consumption, and there was no family history of MD.
Lipomatoses.
Ann Endocrinol (Paris)
June 2024
CHU Lille, Endocrinology, Diabetology and Metabolism, 59000 Lille, France; University Lille, 59000 Lille, France; Inserm U1190, 59000 Lille, France; Competence center PRISIS, Endocrinology and Metabolism Department, CHU, Lille, France. Electronic address:
Article Synopsis
- * These conditions can arise in people without obesity, may have genetic links, and usually differ from lipodystrophy syndromes, which involve areas of fat loss.
- * The review discusses various forms of lipomatosis, including isolated conditions like Madelung disease and syndromic forms associated with genetic disorders, and highlights their potential impact on health and appearance.
Madelung's Disease Evolving to Liposarcoma: An Uncommon Encounter.
Life (Basel)
April 2024
Faculty of Medicine and Pharmacy, "Dunarea de Jos" University of Galati, 800008 Galati, Romania.
(1) Background: Madelung's disease-known also as Benign Symmetric Adenolipomatosis (BSA) or Multiple Symmetric Lipomatosis (MSL), is a rare subcutaneous tissue disease characterized by the proliferation of non-encapsulated fat tissue with mature adipocytes. Patients develop symmetrical fatty deposits of varying sizes, (located particularly around the neck, shoulders, upper and middle back, arms, abdomen, and thighs), having clinical, esthetic, and psychiatric repercussions. (2) Methods: We report a case diagnosed with BSA upon admission to the Neurological and Internal Medicine Departments of the Emergency Clinical Hospital of Galati.
View Article and Find Full Text PDFShedding Light on Multiple Symmetric Lipomatosis: An Overlooked Syndrome in the Evaluation of Obesity.
Am J Case Rep
December 2023
Department of Endocrinology, Diabetes, and Metabolism, Santo António University Hospital Center, Porto, Portugal.
BACKGROUND Multiple symmetric lipomatosis (MSL), also known as Launois-Bensaude syndrome, is a rare syndrome that is frequently misinterpreted as simple obesity. It has seldom been reported. Both conditions can coexist; however, unlike common obesity, in which total body fat is well distributed, patients affected by MSL present with symmetrical, painless fat masses that predominantly appear in the face, neck, occipital region and supraclavicular fossa.
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