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Efficacy of Molecular Methods for the Diagnosis of Enteropathogenic Microorganisms Associated with Diarrhoea: A Systematic Review.
J Gastrointestin Liver Dis
December 2024
Unidad Central del Valle del Cauca-UCEVA, Tuluá, Valle del Cauca, Colombia.
Background And Aims: Diarrhoea has a significant health impact and requires accurate diagnostic approaches, despite the limitations of many existing methods. This review examines various molecular techniques aimed at facilitating the rapid diagnosis of diarrhoeal diseases caused by bacterial, viral and parasitic pathogens.
Methods: A comprehensive systematic literature review was conducted using six prestigious databases, including WOS, Scopus, Science Direct, Embase, PubMed and LILACS Plus.
Irreversible neurological manifestations in undiagnosed disseminated gonococcal infection.
BMJ Case Rep
September 2024
Department of Neurology, Penn State College of Medicine, Hershey, Pennsylvania, USA.
Article Synopsis
- Neisseria gonorrhoeae causes a common STI that can range from mild symptoms to severe complications like pelvic inflammatory disease and septic arthritis.
- A young woman initially presented with fever and joint pain, leading to a diagnosis of inflammatory arthritis following immune suppressing treatments, which resulted in further neurological symptoms and muscle issues.
- Testing revealed a positive urine gonorrhoeae PCR and septic arthritis; she was treated with antibiotics but showed only slow, incomplete recovery.
Domain-Agnostic Representation of Side-Channels.
Entropy (Basel)
August 2024
School of Information Technology, Deakin University, Geelong 3216, Australia.
Side channels are unintended pathways within target systems that leak internal target information. Side-channel sensing (SCS) is the process of exploiting side channels to extract embedded target information. SCS is well established within the cybersecurity (CYB) domain, and has recently been proposed for medical diagnostics and monitoring (MDM).
View Article and Find Full Text PDFAltered epidemiological patterns of Respiratory Syncytial Virus and influenza detections in a tropical Australian setting 2020 to 2023.
Aust N Z J Public Health
August 2024
Territory Pathology, Royal Darwin Hospital, Australia; Clinical Microbiologist and Director of Pathology, Territory Pathology, Royal Darwin Hospital, Australia.
Background: We describe the recent temporal patterns of respiratory syncytial virus (RSV) and influenza virus detections in the Northern Territory (NT) of Australia, between 2020 and 2023.
Methods: This retrospective analysis of patients presenting with respiratory diseases utilised a multiplex viral nucleic acid detection assay for RSV, influenza and SARS Cov2 (COVID-19) to determine the relative frequency of non-COVID-19 respiratory viral detections by age and month during the study period.
Results: During this period of the NT COVID-19 epidemic, disruption of the usual annual wet season RSV outbreak patterns occurred, and the yearly influenza peak was absent for two annual cycles.
Sustained transmission over two decades of a previously unrecognised MPT64 negative strain in Queensland, Australia: a whole genome sequencing study.
Lancet Reg Health West Pac
June 2024
Queensland Mycobacterium Reference Laboratory, Brisbane, Queensland, Australia.
Background: MPT64 is a key protein used for (MTB) complex strain identification. We describe protracted transmission of an MPT64 negative MTB strain in Queensland, Australia, and explore genomic factors related to its successful spread.
Methods: All MPT64 negative strains identified between 2002 and 2022 by the Queensland Mycobacteria Reference Laboratory, and an additional 2 isolates from New South Wales (NSW), were whole genome sequenced.
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