Human fetal tissue is critical for biomedical research.

Stem Cell Reports

Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.

Published: December 2023

AI Article Synopsis

  • - Human fetal tissue and cells are essential for biomedical research, particularly in studying normal development, developmental disorders, and infectious diseases.
  • - They play a significant role in vaccine development and production, showcasing their broad applications in health science.
  • - Fetal cells have unique advantages, such as better growth capacity and survival in laboratory conditions, compared to adult cells, making them valuable for research and medical advancements.

Article Abstract

Human fetal tissue and cells derived from fetal tissue are crucial for biomedical research. Fetal tissues and cells are used to study both normal development and developmental disorders. They are broadly applied in vaccine development and production. Further, research using cells from fetal tissue is instrumental for studying many infectious diseases, including a broad range of viruses. These widespread applications underscore the value of fetal tissue research and reflect an important point: cells derived from fetal tissues have capabilities that cells from other sources do not. In many cases, increased functionality of cells derived from fetal tissues arises from increased proliferative capacity, ability to survive in culture, and developmental potential that is attenuated in adult tissues. This review highlights important, representative applications of fetal tissue for science and medicine.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10724055PMC
http://dx.doi.org/10.1016/j.stemcr.2023.10.008DOI Listing

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