Raf protomers: Drug binding preferences in living cells.

Cell Chem Biol

Division of Chemical Biology and Medicinal Chemistry, The University of Texas at Austin, Austin, TX 78712, USA. Electronic address:

Published: November 2023

The precise and selective quantification of drug-target interactions within the context of RAS-RAF heterodimers in live cells offers a powerful tool for drug development and personalized medicine, particularly in cancer research, where the RAS-RAF pathway is pivotal.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10954368PMC
http://dx.doi.org/10.1016/j.chembiol.2023.10.002DOI Listing

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