AI Article Synopsis

  • - A 48-year-old woman with a history of bladder paraganglioma underwent an 18 F-FDOPA PET/CT scan to investigate possible colorectal paraganglioma and showed significant activity in the colorectal area.
  • - Despite the scan suggesting a neuroendocrine tumor, histological analysis revealed she actually had moderately differentiated colorectal adenocarcinoma.
  • - The study indicates that colorectal adenocarcinoma can lead to false-positive results with the 18 F-FDOPA scan, highlighting the need for further morphological analysis, and it suggests that this marker may indicate the tumor's aggressiveness.

Article Abstract

We present a case of a 48-year-old woman who had previously undergone surgical resection for bladder paraganglioma. An 18 F-FDOPA PET/CT scan performed for suspected colorectal paraganglioma showed intense colorectal uptake associated with adenopathy. Histological examination did not support the presence of a neuroendocrine tumor but instead confirmed the presence of moderately differentiated colorectal adenocarcinoma. Colorectal adenocarcinoma belongs to the list of nonneuroendocrine false-positive tumors that can be detected using 18 F-FDOPA. Therefore, a morphological analysis is important. Thus, 18 F-FDOPA may be a marker for the aggressiveness of colorectal adenocarcinoma.

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Source
http://dx.doi.org/10.1097/RLU.0000000000004945DOI Listing

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