Purpose: To provide an overview of pediatric pars planitis.
Methods: Narrative literature review.
Results: Pars planitis refers to the idiopathic subset of intermediate uveitis in which there is vitritis along with snowball or snowbank formation occurring in the absence of an associated infection or systemic disease. It is thought to be a T-cell mediated disease with a genetic predisposition. Pars planitis accounts for 5-26.7% of pediatric uveitis cases. Presentation is commonly bilateral but asymmetric, often with insidious onset of floaters and blurred vision. Although pars planitis is known to be a benign form of uveitis in most cases, severe complications secondary to chronic inflammation may arise, with cystoid macular edema being the most common cause of visual morbidity. Mild vitritis in the absence of symptoms, vision loss, or macular edema may be observed. Patients with severe vitritis and/or associated vision-threatening complications require prompt aggressive treatment. A stepladder approach including corticosteroids, immunosuppressive agents, anti‑tumor necrosis factor‑alpha and pars plana vitrectomy and/or laser photocoagulation is the most commonly used method for treatment of pars planitis.
Conclusion: Timely diagnosis and adequate treatment of pediatric pars planitis and associated complications are crucial in order to improve visual outcomes.
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http://dx.doi.org/10.1080/09273948.2023.2279683 | DOI Listing |
Ocul Immunol Inflamm
November 2024
Department of Ophthalmology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Purpose: To retrospectively analyze long-term outcomes of pediatric pars planitis (PP).
Methods: PP was defined as vitreal inflammation with snowbank or snowball formation in the absence of a related disease. Eighty-five eyes of 44 patients were included in this study.
Ocul Immunol Inflamm
October 2024
Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Retina
October 2024
Department of Ophthalmology, University of Colorado School of Medicine, Aurora, Colorado.
Ocul Immunol Inflamm
September 2024
Uveitis Service, Eye Protection Foundation Bayrampasa Eye Hospital, Istanbul, Turkey.
Intermediate uveitis is a relatively common form of intraocular inflammation that can be seen at any age. The vitreous is the primary site of inflammation; and the presence of snowballs or snowbank defines its subtype, pars planitis. Since it is a clinical diagnosis, it is important to recognize the typical clinical features and associated ocular complications.
View Article and Find Full Text PDFOcul Immunol Inflamm
July 2024
Department of Ophthalmology, Rabin Medical Center, Petah-Tikva, Israel and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Intermediate uveitis (IU) in an intraocular inflammation that predominantly affects the vitreous. It typically manifests as chronic low-grade inflammation, mainly affecting children and young adults. Uncontrolled chronic intraocular inflammation carries a high risk of visual loss.
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