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D-PRISM: a global survey-based study to assess diagnostic and treatment approaches in pneumonia managed in intensive care.
Crit Care
November 2024
Division of Perioperative, Acute, Critical Care and Emergency Medicine, Department of Medicine, University of Cambridge, Level 4, Addenbrooke's Hospital, Hills Road, Cambridge, UK.
Article Synopsis
- The D-PRISM study investigated global practices for diagnosing and treating pneumonia in ICU settings, focusing on community-acquired, hospital-acquired, and ventilator-associated pneumonia across different countries.
- A survey gathered responses from 1,296 ICU clinicians across 72 countries, revealing varied diagnostic processes and a lack of standardized microbiological testing, particularly in lower-income regions.
- Findings indicated that the typical antibiotic treatment duration was 5-7 days, with shorter durations linked to effective antimicrobial stewardship programs in higher-income countries.
In-hospital unfavorable outcomes of MIS-C during 2020-2022: a systematic review.
Eur J Pediatr
December 2024
Grupo de Investigación Neurociencias, Metabolismo, Efectividad Clínica y Sanitaria (NEMECS), Universidad Científica del Sur, Lima, Perú.
Unlabelled: Studies on the severity in multisystem inflammatory syndrome in children (MIS-C) show heterogeneous results and may not reflect a global perspective. This systematic review aims to estimate the frequency of in-hospital unfavorable outcomes in patients with MIS-C over the 3 years since the onset of the SARS-CoV-2 pandemic. A systematic search was conducted in Medline, Scopus, Embase, Cochrane, Web of Science, Scielo, and preprint repositories until December 15, 2022.
View Article and Find Full Text PDFLumbar Sympathetic Block to Treat CRPS in an 18-Month-Old Girl: A Breaking Barriers Case Report and Review of Literature.
Pain Ther
December 2024
Fondazione Paolo Procacci, 00193, Rome, Italy.
Article Synopsis
- Children under 3 years old, like the 18-month-old girl in this report, can suffer from complex regional pain syndrome (CRPS), causing significant functional and psychological issues.
- The girl experienced severe pain in her right lower limb without any prior trauma, and conventional treatments were ineffective until she underwent a lumbar sympathetic block (LSB) procedure.
- The LSB was successful, leading to substantial pain relief, improved sleep, weight gain, and the start of rehabilitation after the procedure, indicating its potential effectiveness in young patients.
Short-term outcomes of asphyxiated neonates depending on requirement for transfer in the first 24 h of life.
Resuscitation
September 2024
Department of Pediatrics I, Neonatology, Pediatric Intensive Care Medicine, Pediatric Neurology, and Pediatric Infectious Diseases, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; C-TNBS, Centre for Translational Neuro- and Behavioural Sciences, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Importance: In neonates with birth asphyxia (BA) and hypoxic-ischemic encephalopathy, therapeutic hypothermia (TH), initiated within six hours, is the only safe and established neuroprotective measure to prevent secondary brain injury. Infants born outside of TH centers have delayed access to cooling.
Objective: To compare in-hospital mortality, occurrence of seizures, and functional status at discharge in newborns with BA depending on postnatal transfer for treatment to another hospital within 24 h of admission (transferred (TN) versus non-transferred neonates (NTN)).
Sex differences in the SOFA score of ICU patients with sepsis or septic shock: a nationwide analysis.
Crit Care
June 2024
Intensive Care Unit, Department of Acute Medicine, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland.
Article Synopsis
- The study investigates sex-specific differences in organ dysfunction among ICU patients with sepsis or septic shock using the SOFA score.
- An analysis of 5,947 patients showed that women had a lower mean total SOFA score on admission compared to men, influenced particularly by coagulation, liver, and renal components.
- Although significant differences were observed, there were no notable variations in ICU length of stay or mortality rates between sexes, suggesting the need for reevaluation of SOFA scoring criteria based on sex.
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