Utilization of anti-obesity agents is rising in reproductive-age females with some planning for future pregnancy. Lifestyle-induced weight loss has been shown to increase spontaneous conception rate, improve rates of fertility intervention complications, and decrease pregnancy comorbidities. However, the definitive role of assisting weight loss with medication prior to pregnancy remains to be established. The implications of anti-obesity agent used prior to pregnancy are explored in this narrative review, considering benefits of weight loss as well as available evidence for use and risks of anti-obesity agents prior to pregnancy.
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Cumulative effects of extreme ambient temperatures on placental perfusion and function markers in early pregnancy: analysis from a birth cohort study.
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School of Public Health, Nanjing Medical University, Nanjing, China; Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, China. Electronic address:
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