Objectives: In 2020, Brazil experienced two concurrent public health challenges related to respiratory disease: wildfires and increased mortality due to the coronavirus (COVID-19) pandemic. Smoke from these wildfires contributed to a variety of air pollutants, including fine particulate matter (PM). The present study aims to investigate the effects of environmental and socio-economic factors on COVID-19 hospitalisation in the Pantanal.
Study Design: Ecological retrospective study.
Methods: We applied a multilevel negative binomial model to relate monthly hospitalisation data with environmental variables.
Results: We showed that monthly PM concentration levels had the greatest influence on the increase in hospitalisations by COVID-19 in the elderly (23 % increase). The Gini index, a coefficient that reflects income inequalities, also had a positive association with COVID-19 hospitalisations (18 % increase). Higher temperatures and humidity were protective factors, showing a 15 % and 14 % decrease in hospitalisations, respectively. The results of the present study suggest that high PM exposure contributed to the increase in COVID-19 hospitalisations, as did the social inequalities of each municipality.
Conclusions: The present study highlights the importance of gathering evidence supported by multiple information sources to guide decision-making and identify populations needing better public health systems.
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http://dx.doi.org/10.1016/j.puhe.2023.10.032 | DOI Listing |
J Microbiol Immunol Infect
March 2025
Division of Pediatric Infectious Diseases, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan; Chang Gung University School of Medicine, Taoyuan, Taiwan. Electronic address:
Background: Strict mask wearing and handwashing were implemented in hospital settings during COVID-19 pandemic in Taiwan. To explore if nasal methicillin-resistant Staphylococcus aureus (MRSA) carriage rate among inpatients in the hospital changed before and after COVID-19, we conducted this study.
Methods: Patients who were admitted to a regional hospital in central Taiwan during one week in 2012 and 2023, respectively, were enrolled.
Trop Med Int Health
March 2025
UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, Australia.
Background: To demonstrate the application and utility of geostatistical modelling to provide comprehensive high-resolution understanding of the population's protective immunity during a pandemic and identify pockets with sub-optimal protection.
Methods: Using data from a national cross-sectional household survey of 6620 individuals in the Dominican Republic (DR) from June to October 2021, we developed and applied geostatistical regression models to estimate and predict Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) spike (anti-S) antibodies (Ab) seroprevalence at high resolution (1 km) across heterogeneous areas.
Results: Spatial patterns in population immunity to SARS-CoV-2 varied across the DR.
J Prof Nurs
March 2025
American Association of Colleges of Nursing, United States of America.
Background: Nurse faculty play a critical role in sustaining the nursing workforce and meeting the nation's healthcare needs. Given the ongoing concerns about faculty supply, ensuring the well-being of nurse educators is critical concern for academic institutions and the larger nursing profession.
Purpose: This study was conducted to assess the level of well-being among nursing faculty in undergraduate and graduate programs.
Int J Pharm
March 2025
Bioinformatics Center of AMMS, Beijing, People's Republic of China. Electronic address:
Traditional mRNA vaccine formulation loaded by lipid nanoparticle (mRNA-LNP) has several shortcomings in clinical application, including the need for cryopreservation, discomfort associated with intramuscular injections, and the risk of liver aggregation. Dissolvable microneedles (DMNs), as a novel transdermal drug delivery platform, can overcome the skin barrier to deliver drugs directly into the skin in a minimally invasive manner. However, mRNA-LNP is unstable and easily degraded during the solidification of DMN.
View Article and Find Full Text PDFJ Obstet Gynaecol Can
March 2025
Creighton University School of Medicine, Omaha Campus, Department of Clinical Research and Evaluative Sciences).
COVID-19 outcomes are worse in non-pregnant patients that are cystic fibrosis carriers; however, no studies have examined COVID-19 outcomes in pregnant patients that are cystic fibrosis carriers. We evaluated the cystic fibrosis carrier status of pregnant patients with COVID-19 in three geographical regions in the United States and compared outcomes between non-carriers and carriers. Out of 2430 pregnant patients with COVID-19, 229 had a cystic fibrosis screen.
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