The quest for the optimal biomarker: is extending the spectrum of targeted mutations in breast cancer carcinoma worthwhile?

Ann Transl Med

Institut régional du Cancer de Montpellier (ICM), INSERM U1194, Montpellier University, Montpellier, France.

Published: October 2023

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632578PMC
http://dx.doi.org/10.21037/atm-23-1608DOI Listing

Publication Analysis

Top Keywords

quest optimal
4
optimal biomarker
4
biomarker extending
4
extending spectrum
4
spectrum targeted
4
targeted mutations
4
mutations breast
4
breast cancer
4
cancer carcinoma
4
carcinoma worthwhile?
4

Similar Publications

Improving the performance of metasurface optical elements has become an increasingly important element of the ongoing quest toward their practical applications. One of the primary challenges is how to suppress light reflections across an entire metasurface. Such reflections are the source of undesirable noise, so their suppression is especially critical in imaging and optical communication applications.

View Article and Find Full Text PDF

Artificial neural networks (ANNs) are one of the most promising tools in the quest to develop general artificial intelligence. Their design was inspired by how neurons in natural brains connect and process, the only other substrate to harbor intelligence. Compared to biological brains that are sparsely connected and that form sparsely distributed representations, ANNs instead process information by connecting all nodes of one layer to all nodes of the next.

View Article and Find Full Text PDF

Left atrial shunting devices: why, what, how, and… when?

Heart Fail Rev

January 2025

Department of Cardiology, San Luca Hospital, IRCCS Istituto Auxologico Italiano, Milan, Italy.

Left atrial (LA) hypertension is central in the pathophysiology of heart failure (HF) in general and of HF with preserved ejection fraction (HFpEF) in particular. Despite approved treatments, a number of HF patients continue experiencing disabling symptoms due to LA hypertension, causing pulmonary congestion, pulmonary hypertension, and right heart dysfunction, at rest and/or during exercise. LA decompression therapies, i.

View Article and Find Full Text PDF

Involving people with lived experience when setting cerebral palsy research priorities: A scoping review.

Dev Med Child Neurol

January 2025

Cerebral Palsy Alliance Research Institute, Specialty of Child and Adolescent Health, Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.

Aim: To describe research priority-setting activities for cerebral palsy (CP) that have been conducted worldwide involving people with lived experience, focusing on participant characteristics, methods employed, identified research priorities, and collaboration as research partners.

Method: The JBI scoping review approach was followed. Six electronic databases and grey literature were searched for all publications up to February 2024.

View Article and Find Full Text PDF

Review on application of silk fibroin hydrogels in the management of wound healing.

Int J Biol Macromol

January 2025

State Key Laboratory of Resource Insects, Southwest University, Chongqing 400716, China. Electronic address:

Wounds are regarded as disruptions in the integrity of human skin tissues, and the process of wound healing is often characterized as protracted and complex, primarily due to the potential infection or inflammation caused by microorganisms. The quest for innovative solutions that accelerate wound healing while prioritizing patient safety and comfort has emerged as a focal point. Within this pursuit, silkworm silk fibroin-a natural polymer extracted from silk cocoons-exhibits a distinctive combination of properties including biocompatibility, biodegradability, superior mechanical strength, water absorption, and low immunogenicity, which align closely with the demands of contemporary wound care.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!