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| http://dx.doi.org/10.4103/aian.aian_611_23 | DOI Listing |
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The Clinical Neuroscience of Lucid Dreaming.
Neurosci Biobehav Rev
January 2025
Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.
During most dreams, the dreamer does not realize that they are in a dream. In contrast, lucid dreaming allows to become aware of the current state of mind, often accompanied by considerable control over the ongoing dream episode. Lucid dreams can happen spontaneously or be induced through diverse behavioural, cognitive or technological strategies.
View Article and Find Full Text PDFOcrelizumab dose selection for treatment of pediatric relapsing-remitting multiple sclerosis: results of the OPERETTA I study.
J Neurol
January 2025
Division of Child Neurology, Children's Hospital of Philadelphia, Departments of Neurology and Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Background: The presented study identified the appropriate ocrelizumab dosing regimen for patients with pediatric-onset multiple sclerosis (POMS).
Methods: Patients with POMS aged 10-17 years were enrolled into cohort 1 (body weight [BW] < 40 kg, ocrelizumab 300 mg) and cohort 2 (BW ≥ 40 kg, ocrelizumab 600 mg) during a 24-week dose-exploration period (DEP), followed by an optional ocrelizumab (given every 24 weeks) extension period.
Primary Endpoints: pharmacokinetics, pharmacodynamics (CD19 B-cell count); secondary endpoint: safety; exploratory endpoints: MRI activity, protocol-defined relapses, Expanded Disability Status Scale (EDSS) score change.
A systematic Review of Spirituality Tools Based on Psychometric Qualities and Recommendations for Future Research.
J Relig Health
December 2024
Department of Yoga and Spirituality, SVYASA University, Prashanti Kutiram, Vivekanand Road, Kallubalu Post Jigani, Anekal Taluk, Bangalore, 560105, India.
Spiritual lifestyles positively impact physical and mental health, which can be addressed by effective spiritual tools. This review systematically evaluates general spirituality instruments retrieved from various databases. Among the top four validated tools with strong psychometric properties, each exhibited a limitation-such as contamination, absence of subscales, or lack of confirmatory factor analysis-which impacts their broader applicability.
View Article and Find Full Text PDFSystematic review of the efficacy of yoga and mindfulness in the management of pediatric obesity.
Ann N Y Acad Sci
December 2024
Department of Nutrition Sciences and Department of Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama, USA.
The neuroplasticity of adolescents could make them responsive to interventions affecting brain maturation such as yoga and mindfulness. We aimed to determine their efficacy and safety for the management of children and adolescents with obesity. A systematic search using MEDLINE, EMBASE, and PsycInfo was performed up to March 2024.
View Article and Find Full Text PDFThe Role of Spirituality and Religion in Improving Quality of Life and Coping Mechanisms in Cancer Patients.
Healthcare (Basel)
November 2024
Department of Oncology, Victor Babes University of Medicine and Pharmacy, Bd. Victor Babes No. 16, 300226 Timisoara, Romania.
Background/objectives: This systematic review aimed to comprehensively evaluate the role of spirituality and religion in the journey of patients with cancer and assess their impact on various aspects of well-being and coping mechanisms.
Methods: Systematic searches were conducted in PubMed, Scopus, and Google Scholar following the PRISMA guidelines. This study focused on the period from 2014 to 2024, the time chosen for the emerging integration of spirituality and religion in cancer treatment.
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