Previous studies have used cardiopulmonary exercise test (CPET) data to objectively assess physiological changes in patients undergoing percutaneous pulmonary valve implantation. A retrospective review was performed to assess pre- and post-CPET data among patients undergoing Alterra Adaptive Prestent and SAPIEN 3 transcatheter heart valve (Alterra) placement. Of the 7 patients eligible for the study, 5 (71%) were male. The mean age was 22 years (range: 12-49 years). CPET data showed significant ( = 0.03) improvement in ventilatory efficiency (V/V) while only 2 (29%) patients had an improvement of percent predicted peak oxygen consumption (V). These findings suggest favourable haemodynamic changes though further investigation is needed.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642079PMC
http://dx.doi.org/10.1016/j.cjcpc.2022.06.002DOI Listing

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