A case of junctional epidermolysis bullosa intermediate with collagen XVII deficiency treated with dupilumab.

J Dermatolog Treat

Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, P.R. China.

Published: December 2023

Inherited epidermolysis bullosa is a heterogeneous group of hereditary skin diseases characterized by skin (mucosa) fragility, which leads to blistering. Junctional epidermolysis bullosa is associated with mutations in genes expressing proteins of the dermo-epidermal junction. Dupilumab, an antibody that directly targets interleukin (IL)-4 receptor alpha, may be an effective treatment for dystrophic epidermolysis bullosa. We describe a case of junctional epidermolysis bullosa that improved with dupilumab.

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Source
http://dx.doi.org/10.1080/09546634.2023.2253943DOI Listing

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