In this article, a new unsupervised contrastive clustering (CC) model is introduced, namely, image CC with self-learning pairwise constraints (ICC-SPC). This model is designed to integrate pairwise constraints into the CC process, enhancing the latent representation learning and improving clustering results for image data. The incorporation of pairwise constraints helps reduce the impact of false negatives and false positives in contrastive learning, while maintaining robust cluster discrimination. However, obtaining prior pairwise constraints from unlabeled data directly is quite challenging in unsupervised scenarios. To address this issue, ICC-SPC designs a pairwise constraints learning module. This module autonomously learns pairwise constraints among data samples by leveraging consensus information between latent representation and pseudo-labels, which are generated by the clustering algorithm. Consequently, there is no requirement for labeled images, offering a practical resolution to the challenge posed by the lack of sufficient supervised information in unsupervised clustering tasks. ICC-SPC's effectiveness is validated through evaluations on multiple benchmark datasets. This contribution is significant, as we present a novel framework for unsupervised clustering by integrating contrastive learning with self-learning pairwise constraints.
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http://dx.doi.org/10.1109/TNNLS.2023.3329494 | DOI Listing |
ISME J
December 2024
Université Paris Cité, INSERM, IAME, 75018 Paris, France.
Escherichia coli is an increasingly antibiotic-resistant opportunistic pathogen. Few data are available on its ecological and evolutionary dynamics in its primary commensal niche, the vertebrate gut. Using Illumina and/or Nanopore technologies, we sequenced whole genomes of 210 E.
View Article and Find Full Text PDFEcology
December 2024
Wildlife Research and Monitoring Section, Ministry of Natural Resources and Forestry, Peterborough, Ontario, Canada.
Animals within social groups respond to costs and benefits of sociality by adjusting the proportion of time they spend in close proximity to other individuals in the group (cohesion). Variation in cohesion between individuals, in turn, shapes important group-level processes such as subgroup formation and fission-fusion dynamics. Although critical to animal sociality, a comprehensive understanding of the factors influencing cohesion remains a gap in our knowledge of cooperative behavior in animals.
View Article and Find Full Text PDFElife
December 2024
Department of Biological Sciences, University of Texas at Dallas, Richardson, United States.
Bacterial membranes are complex and dynamic, arising from an array of evolutionary pressures. One enzyme that alters membrane compositions through covalent lipid modification is MprF. We recently identified that MprF synthesizes lysyl-phosphatidylglycerol (Lys-PG) from anionic PG, and a novel cationic lipid, lysyl-glucosyl-diacylglycerol (Lys-Glc-DAG), from neutral glycolipid Glc-DAG.
View Article and Find Full Text PDFJ Biomech
January 2025
Mechanical and Biomedical Engineering, Boise State University, Boise, ID, United States. Electronic address:
bioRxiv
November 2024
Department of Biology, Stanford University, Stanford, CA 94305.
Allele-sharing dissimilarity (ASD) statistics are measures of genetic differentiation for pairs of individuals or populations. Given the allele-frequency distributions of two populations-possibly the same population-the expected value of an ASD statistic is computed by evaluating the expectation of the pairwise dissimilarity between two individuals drawn at random, each from its associated allele-frequency distribution. For each of two ASD statistics, which we term and , we investigate the extent to which the expected ASD is constrained by allele frequencies in the two populations; in other words, how is the magnitude of the measure bounded as a function of the frequency of the most frequent allelic type? We first consider dissimilarity of a population with itself, obtaining bounds on expected ASD in terms of the frequency of the most frequent allelic type in the population.
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