Some controversial reports have observed oxygen desaturation (defined as percutaneous oxygen saturation (SpO) < 90%) during electroconvulsive therapy (ECT). The purpose of this pilot study was to examine oxygenation states in eight patients during ECT. In addition to the usual hemodynamic monitors and pulse oximeter, the oxygen reserve index (ORi) was monitored using a pulse oximeter. Patients received either no preoxygenation or preoxygenation with 100% oxygen via a tight-fitting mask for 1 or 3 min before induction of anesthesia. ORi increased after preoxygenation. ORi differed significantly between 3 min of preoxygenation and the other two methods before restarting mask ventilation. SpO was significantly increased with all methods before stopping manual mask ventilation or before restarting manual mask ventilation compared with that before preoxygenation. No oxygen desaturation was observed at any time with any treatment methods. In nonobese patients, the adequate oxygenation state as shown by SpO and ORi was maintained during ECT even without preoxygenation.
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http://dx.doi.org/10.1155/2023/7807693 | DOI Listing |
Water Res
December 2024
Department of Sanitation and Environmental Engineering, School of Engineering, Federal University of Minas Gerais, Avenue Antônio Carlos, 6627, Campus Pampulha, Belo Horizonte, MG, Brazil. Electronic address:
Arsenic (As) enrichment in groundwater stems from natural and hydrogeochemical factors, leading to geological contamination. Groundwater and surface water are interconnected, allowing As migration and surface water contamination. The As contamination poses health risks through contaminated water consumption.
View Article and Find Full Text PDFExtracorporeal membrane oxygenation (ECMO) is a lifesaving treatment for critically ill patients in cardiac or respiratory failure refractory to conventional treatment. Patients on an ECMO circuit (pump, oxygenator, tubing) require numerous medications including sedatives, analgesics, cardioactive medications, and anticonvulsants. Currently, there are few dosing guidelines to optimize pharmacotherapy in this situation.
View Article and Find Full Text PDFDiscov Med
December 2024
Department of Biochemistry and General Chemistry, Medical College of the University of Rzeszów, 35-959 Rzeszów, Poland.
Photodynamic therapy (PDT) is emerging as a promising treatment for many diseases. This non-invasive approach uses photosensitizing agents and light to selectively destroy abnormal cells, providing a valuable alternative to traditional treatments. Scientists are investigating the use of PDT in various areas of the head, and their work is focused on a growing number of new discoveries and methods for treating cancer.
View Article and Find Full Text PDFPediatr Crit Care Med
December 2024
Haematology Research, Murdoch Children's Research Institute, Melbourne, VIC, Australia.
Objectives: To determine if a priori standardization of outcome hemostatic definitions alone was adequate to enable useful comparison between two cohorts of pediatric extracorporeal membrane oxygenation (ECMO) patients, managed according to local practice and protocol.
Design: Comparison of two separate prospective cohort studies performed at different centers with standardized outcome definitions agreed upon a priori.
Setting: General and cardiac PICUs at the Royal Children's Hospital (RCH) in Melbourne, Australia, and the Sophia Children's Hospital (SCH) in Rotterdam, The Netherlands.
ASAIO J
October 2024
From the Division of Cardiovascular Critical Care, Department of Cardiology, Boston Children's Hospital, Boston, Massachusetts.
Patients with restrictive cardiomyopathy (RCM) and hypertrophic cardiomyopathy (HCM) were previously considered poor candidates for mechanical circulatory support due to technical limitations related to restrictive ventricular physiology and small ventricular size, limiting the ability to provide adequate flows and decompress the heart. Literature examining use of extracorporeal membrane oxygenation (ECMO) in this population consists of a single case series reporting no survivors. We report our experience providing ECMO in children with RCM or HCM at a large pediatric quaternary cardiac center.
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