Cortical circuit dynamics underlying motor skill learning: from rodents to humans.

Front Mol Neurosci

Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA, United States.

Published: October 2023

Motor learning is crucial for the survival of many animals. Acquiring a new motor skill involves complex alterations in both local neural circuits in many brain regions and long-range connections between them. Such changes can be observed anatomically and functionally. The primary motor cortex (M1) integrates information from diverse brain regions and plays a pivotal role in the acquisition and refinement of new motor skills. In this review, we discuss how motor learning affects the M1 at synaptic, cellular, and circuit levels. Wherever applicable, we attempt to relate and compare findings in humans, non-human primates, and rodents. Understanding the underlying principles shared by different species will deepen our understanding of the neurobiological and computational basis of motor learning.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641381PMC
http://dx.doi.org/10.3389/fnmol.2023.1292685DOI Listing

Publication Analysis

Top Keywords

motor learning
12
motor skill
8
brain regions
8
motor
7
cortical circuit
4
circuit dynamics
4
dynamics underlying
4
underlying motor
4
learning
4
skill learning
4

Similar Publications

Objectives: To examine the effect of integrated motor learning clinical pilates protocol we developed for patients with Parkinson's Disease (pwPD) on providing enduring motor skills in walking, balance, reaction time, cadence, and functional mobility at 3-months follow-up.

Design: A parallel-group, randomized controlled trial (RCT).

Setting: XXX Medical Center, XXX, and XXX Physiotherapy and Rehabilitation Center, Nicosia.

View Article and Find Full Text PDF

Families' experiences and perspectives on the early use of powered mobility in children with spinal muscular atrophy type I in the natural context.

Disabil Rehabil Assist Technol

March 2025

Faculty of Physiotherapy and Nursing. Department of Nursing, Physiotherapy and Occupational Therapy, Universidad de Castilla-La Mancha, Toledo, Spain.

Purpose: To describe the experiences of parents who used powered mobility in children with Spinal Muscular Atrophy, SMA type I,at an early age in the natural context like a family-centered program, using inductive qualitative content analysis.

Materials And Methods: This qualitative study was embedded within a single-blinded randomized waiting list controlled clinical trial, which involved 16 children with SMA type I. This study specifically explores the experiences of the 9 parents whose children participated in the intervention group and completed the training.

View Article and Find Full Text PDF

Toward autonomous event-based sensorimotor control with supervised gait learning and obstacle avoidance for robot navigation.

Front Neurosci

February 2025

Department of Electrical and Computer Engineering (ECE), Swanson School of Engineering, University of Pittsburgh, Pittsburgh, PA, United States.

Miniature robots are useful during disaster response and accessing remote or unsafe areas. They need to navigate uneven terrains without supervision and under severe resource constraints such as limited compute, storage and power budget. Event-based sensorimotor control in edge robotics has potential to enable fully autonomous and adaptive robot navigation systems capable of responding to environmental fluctuations by learning new types of motion and real-time decision making to avoid obstacles.

View Article and Find Full Text PDF

Parameter optimization of 3D convolutional neural network for dry-EEG motor imagery brain-machine interface.

Front Neurosci

February 2025

Department of Precision Machinery Engineering, College of Science and Technology, Nihon University, Funabashi, Chiba, Japan.

Easing the behavioral restrictions of those in need of care not only improves their own quality of life (QoL) but also reduces the burden on care workers and may help reduce the number of care workers in countries with declining birthrates. The brain-machine interface (BMI), in which appliances and machines are controlled only by brain activity, can be used in nursing care settings to alleviate behavioral restrictions and reduce stress for those in need of care. It is also expected to reduce the workload of care workers.

View Article and Find Full Text PDF

Introduction: The onset of locomotion is a critical motor milestone in early childhood and increases engagement with the environment. Toddlers with neurodevelopmental disabilities often have atypical motor development that impacts later outcomes. Video-based gait analysis using pose estimation offers an alternative to standardized motor assessments which are subjective and difficult to ascertain in some populations, yet very little work has been done to determine its accuracy in young children.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!