AI Article Synopsis

  • Hepatoid adenocarcinoma of lung (HAL) is a rare and aggressive cancer that resembles liver cancers and often produces high levels of alpha-fetoprotein (AFP).
  • The case involved a male patient in his 40s with a history of smoking who experienced fever, weight loss, cough, and anorexia, initially being treated for tuberculosis.
  • Despite treatment, his condition deteriorated rapidly, leading to a pulmonary embolism and ultimately death, with a postmortem biopsy confirming the presence of HAL.

Article Abstract

Hepatoid adenocarcinoma of lung (HAL) is a rare aggressive malignant tumour which histologically resembles hepatocellular carcinoma (HCC). Hepatoid adenocarcinoma (HAC) mostly produces high levels of alphafetoprotein (AFP) and is frequently found in extrahepatic organs including stomach, testes, ovaries, lungs and pancreas. Our patient was a male in his 40s with a chronic smoking history, presented with complaints of fever, weight loss, cough and anorexia for one month. On the basis of history, examination and initial investigation patient were started on empirical antitubercular therapy. However, within a span of 10 days, patient's condition worsened, and he developed a pulmonary embolism, which despite adequate treatment did not improve and the patient succumbed to his illness. Postmortem biopsy revealed a rare primary lung tumour, HAL.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10723204PMC
http://dx.doi.org/10.4103/lungindia.lungindia_117_23DOI Listing

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