AI Article Synopsis
- The study explores how gut microorganisms affect obesity and evaluates the impact of combining a specific treatment (PENS T6) with a low-calorie diet and probiotics on weight loss and metabolic health.
- It involves a group of adults with obesity (BMI > 30 kg/m) split into two: one receiving the PENS T6 and diet alone, and another receiving the same along with probiotics.
- Results showed that the addition of probiotics enhances weight loss and improves glycemic and lipid profiles while also positively influencing gut microbiota related to obesity.
Article Abstract
The pathogenesis of obesity has been linked to alterations in gut microorganisms. The aim of this study was to investigate the effect of , together with PENS T6 and a hypocaloric diet, on weight loss, hypertension and laboratory glycemic and lipid profile. A prospective non-randomized study was conducted involving adult patients with a body mass index (BMI) > 30 kg/m. Patients were divided into two groups: those undergoing PENS-T6 and hypocaloric diet (PENS-Diet Group) and those undergoing the same PENS-T6 scheme and hypocaloric diet, but additionally receiving probiotics including (PENS-Diet + Group). Weight loss was assessed at the end of the treatment, and analytical glycemic and lipid profile, and microbiological analysis of feces were performed before and after treatment. The addition of to PENS T6 and a low-calorie diet, increases weight loss and further improves the glycemic and lipid profile. also causes a further improvement in obesity-associated dysbiosis, mainly by increasing the muconutritive () and regulatory ( spp.) microbiome, and the Phylum Bacteroidetes ( spp.) and decreasing the / ratio.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649111 | PMC |
| http://dx.doi.org/10.3390/nu15214549 | DOI Listing |
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