AI Article Synopsis
- High-frequency ultrasound can help differentiate between high-risk and low-risk dermatofibromas, providing crucial internal information about these lesions.
- A study analyzed 50 dermatofibromas, categorizing them based on ultrasound features and their pathological risk levels.
- Key differences were found in characteristics like thickness, shape, and internal echogenicity, with high-risk lesions showing irregular morphology and blood flow, while low-risk ones were mostly regular in appearance with no blood flow.
Article Abstract
Background: Dermatofibroma has various pathological classifications, some of which pose a risk of recurrence and metastasis. Distinguishing these high-risk dermatofibromas based on appearance alone can be challenging. Therefore, high-frequency ultrasound may provide additional internal information on these lesions, helping to identify high-risk and low-risk dermatofibroma early.
Methods: In this retrospective study, 50 lesions were analyzed to explore the correlation between clinical and high-frequency ultrasound features and dermatofibroma risk level. Based on their pathological features, the lesions were divided into high-risk ( = 17) and low-risk ( = 33) groups. Subsequently, an identification model based on significant high-frequency ultrasound features was developed.
Results: Significant differences were observed in the thickness, shape, internal echogenicity, stratum basal, and Doppler vascular patterns between the high-risk and low-risk groups. The median lesion thickness for the high-risk dermatofibroma group was 4.1 mm (IQR: 3.2-6.1 mm), while it was 3.1 mm (IQR: 1.3-4.2 mm) for the low-risk dermatofibroma group. In the high-risk dermatofibroma group, irregular morphology was predominant (70.6%, 12/17), the most common being dermis-to-subcutaneous soft tissue penetration (64.7%, 11/17), and heterogenous internal echogenicity was observed in the majority of cases (76.5%, 13/17). On the other hand, regular morphology was more prevalent in the low-risk dermatofibroma group (78.8%, 26/33), primarily limited to the dermis layer (78.8%, 26/33), with homogeneous internal echogenicity also being prevalent in the majority of cases (81.8%, 27/33). Regarding the Doppler vascularity pattern, 69.7% (23/33) of low-risk dermatofibromas had no blood flow, while 64.7% (11/17) of high-risk dermatofibromas had blood flow.
Conclusion: High-frequency ultrasound is crucial in distinguishing high-risk and low-risk dermatofibromas, making it invaluable for clinical management.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650765 | PMC |
| http://dx.doi.org/10.3390/diagnostics13213305 | DOI Listing |
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