Purpose: Our goal was to compare locations of COVID-19 vaccine provision in urban and rural communities over the course of the pandemic.
Methods: We used the Iowa Immunization Registry Information System (IRIS) to identify the organizations providing COVID-19 vaccines (eg, pharmacies, public health departments, and medical providers). Proportions of first-dose vaccines by organization type and patient census-based statistical area were generated. We calculated Chi-square tests to assess differences among metropolitan, micropolitan, and noncore communities.
Findings: IRIS data revealed that 64% (n = 2,043,251) of Iowans received their first COVID-19 vaccine between December 14, 2020, and December 31, 2022. For metropolitan-dwelling individuals, most first doses were administered at pharmacies (53%), with similar trends observed for micropolitan (49%) and noncore (42%) individuals. The second most common location for metropolitan individuals was medical practices (17%); public health clinics and departments were the second most common provider for micropolitan (26%) and noncore (33%) individuals. These trends shifted over time. In December 2020, hospitals were the most common vaccine provider for everyone, but by December 2022, medical providers were the most common source for metropolitan individuals, and pharmacies were most common for micropolitan and noncore individuals.
Conclusions: Trends in the type of vaccine provider differentiated metropolitan residents from micropolitan and noncore residents. For the latter groups, local public health departments played a more significant role. Across all groups, pharmacists emerged as a critical vaccine provider. Our findings can be used to plan for seasonal vaccine campaigns as well as potential future mass vaccination campaigns.
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http://dx.doi.org/10.1111/jrh.12811 | DOI Listing |
Sci Rep
December 2024
Department of Medical Microbiology, Radboudumc, Nijmegen, The Netherlands.
The aetiology of Alzheimer's disease (AD) and Parkinson's disease (PD) are unknown and tend to manifest at a late stage in life; even though these neurodegenerative diseases are caused by different affected proteins, they are both characterized by neuroinflammation. Links between bacterial and viral infection and AD/PD has been suggested in several studies, however, few have attempted to establish a link between fungal infection and AD/PD. In this study we adopted a nanopore-based sequencing approach to characterise the presence or absence of fungal genera in both human brain tissue and cerebrospinal fluid (CSF).
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December 2024
KAUST Center of Excellence for Smart Health (KCSH), King Abdullah University of Science and Technology, Thuwal, 23955, Saudi Arabia.
Analyzing microbial samples remains computationally challenging due to their diversity and complexity. The lack of robust de novo protein function prediction methods exacerbates the difficulty in deriving functional insights from these samples. Traditional prediction methods, dependent on homology and sequence similarity, often fail to predict functions for novel proteins and proteins without known homologs.
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December 2024
Department of Neurobiology and Behavior, University of California Irvine, Irvine, CA, 92697, USA.
Preserving the ability to vividly recall emotionally rich experiences contributes to quality of life in older adulthood. While prior works suggest that moderate-intensity physical activity (MPA) may bolster memory, it is unclear whether this extends to emotionally salient memories consolidated during sleep. In the current study, older adults (mean age = 72.
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December 2024
MARE - Marine and Environment Sciences Centre/ARNET - Aquatic Research Network, Ispa - Instituto Universitário, Lisboa, Portugal.
While numerous studies have established correlations between parasite load and negative effects on their hosts, establishing causality is more challenging because parasites can directly compromise host condition and survival or simply opportunistically thrive on an already weakened host. Here, we evaluated whether Ixodes uriae, a widespread seabird tick, can cause a decrease in growth parameters (body mass, bill length and growth rates) and survival of chicks of a colonially seabird, the black-browed albatross (Thalassarche melanophris) breeding on New Island (West Falkland). To investigate this, we daily removed the ticks from 28 randomly selected chicks during their first 14 days of life (treated chicks) and compared their growth and survival with 49 chicks of a control group.
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