We introduce a modification to the standard expression for tree-level CP violation in scattering processes at the LHC, which is important when the initial state is not self-conjugate. Based on that, we propose a generic and model-independent search strategy for probing tree-level CP violation in inclusive multilepton signals. We then use TeV-scale 4-fermion operators of the form tuℓℓ and tcℓℓ with complex Wilson coefficients as an illustrative example and show that it may generate O(10%) CP asymmetries that should be accessible at the LHC with an integrated luminosity of O(1000) fb^{-1}.
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