AI Article Synopsis
- * Studies show that the composition of gut bacteria can affect how well patients respond to ICIs, suggesting the potential for using gut microbiome adjustments as a cancer therapy strategy.
- * This review specifically looks at how modifying the gut microbiome—through methods like probiotics or fecal microbiota transplantation (FMT)—can improve responses to ICIs in renal cancer patients.
Article Abstract
The gut microbiome has recently been proposed as a key player in cancer development and progression. Several studies have reported that the composition of the gut microbiome plays a role in the response to immune checkpoint inhibitors (ICIs). The gut microbiome modulation has been investigated as a potential therapeutic strategy for cancer, mainly in patients undergoing therapy with ICIs. In particular, modulation through probiotics, FMT or other microbiome-related approaches have proven effective to improve the response to ICIs. In this review, we examine the role of the gut microbiome in enhancing clinical responses to ICIs in the treatment of renal cancer.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653624 | PMC |
| http://dx.doi.org/10.1080/21645515.2023.2268982 | DOI Listing |
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