tidytcells: standardizer for TR/MH nomenclature.

Front Immunol

Division of Infection and Immunity, Faculty of Medical Sciences, University College London (UCL), London, United Kingdom.

Published: November 2023

T cell receptors (TR) underpin the diversity and specificity of T cell activity. As such, TR repertoire data is valuable both as an adaptive immune biomarker, and as a way to identify candidate therapeutic TR. Analysis of TR repertoires relies heavily on computational analysis, and therefore it is of vital importance that the data is standardized and computer-readable. However in practice, the usage of different abbreviations and non-standard nomenclature in different datasets makes this data pre-processing non-trivial. tidytcells is a lightweight, platform-independent Python package that provides easy-to-use standardization tools specifically designed for TR nomenclature. The software is open-sourced under the MIT license and is available to install from the Python Package Index (PyPI). At the time of publishing, tidytcells is on version 2.0.0.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634431PMC
http://dx.doi.org/10.3389/fimmu.2023.1276106DOI Listing

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