AI Article Synopsis

  • - Cold agglutinin disease is a type of autoimmune hemolytic anemia triggered by specific antibodies that affect red blood cells at low temperatures.
  • - A 46-year-old man with this condition developed complications like pulmonary thrombosis and organizing pneumonia.
  • - Treatment with prednisolone was effective in improving both the cold agglutinin disease and the organizing pneumonia, indicating a potential connection between the two conditions.

Article Abstract

Cold agglutinin disease is a subtype of autoimmune hemolytic anemia that occurs via the activation of specific anti-red blood cell antibodies (agglutinins) at low temperatures. Autoimmune hemolytic anemia has been reported to cause interstitial pneumonia; however, the underlying mechanism remains unclear. We herein report a 46-year-old man diagnosed with cold agglutinin disease complicated by pulmonary thrombosis and organizing pneumonia. Treatment with prednisolone improved the course of cold agglutinin disease and organizing pneumonia in a similar manner. To our knowledge, this is the first report of cold agglutinin associated with organizing pneumonia, suggesting a potential link between the two.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11239267PMC
http://dx.doi.org/10.2169/internalmedicine.2368-23DOI Listing

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