AI Article Synopsis
- Solid-state NMR is an emerging technique providing detailed structural information at atomic resolution in lipid bilayers.
- Two main methods are used for analyzing membrane proteins and peptides: magic angle sample spinning and uniaxially oriented membrane samples.
- The discussion will cover the advancements in these methods and their relevance to structural biology, biomedical research, and membrane biophysics.
Article Abstract
Solid-state NMR is a quickly developing technique that allows one to obtain structural information at atomic resolution in extended lipid bilayers in a rather unique manner. Two approaches have been developed for membrane proteins and peptides namely magic angle sample spinning and the use of uniaxially oriented membrane samples. The state-of-the-art of both approaches will be introduced and the perspectives of solid-state NMR spectroscopy in the context of other structural biology techniques, pressing biomedical questions and membrane biophysics will be discussed.
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| http://dx.doi.org/10.1016/j.bbamem.2023.184162 | DOI Listing |
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